Toward functional glycomics by localization of tissue lectins : immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster.
Toward functional glycomics by localization of tissue lectins : immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster.
Publication date :
21 October 2004
Journal title :
Histochemistry and Cell Biology
ISSN :
0948-6143
Publisher :
Springer, Germany
Volume :
123
Pages :
29-41
Peer reviewed :
Peer Reviewed verified by ORBi
Research unit :
M118 - Histologie
Research institute :
R550 - Institut des Sciences et Technologies de la Santé
Agrwal N, Wang JL, Voss PG (1989) Carbohydrate-binding protein 35. Levels of transcription and mRNA accumulation in quiescent and proliferating cells. J Biol Chem 264:17236-17242
Ahmad N, Gabius HJ, André S, Kaltner H, Sabesan S, Roy R, Liu B, Macaluso F, Brewer CF (2004) Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes. J Biol Chem 279:10841-10847
André S, Kojima S, Yamazaki N, Fink C, Kaltner H, Kayser K, Gabius HJ (1999) Galectins-1 and -3 and their ligands in tumor biology. J Cancer Res Clin Oncol 125:461-474
André S, Pieters RJ, Vrasidas I, Kaltner H, Kuwabara I, Liu FT, Liskamp RMJ, Gabius HJ (2001) Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates. ChemBioChem 2:822-830
André S, Liu B, Gabius HJ, Roy R (2003) First demonstration of differential inhibition of lectin binding by synthetic tri- and tetravalent glycoclusters from cross-coupling of rigidified 2-propynyl lactoside. Org Biomol Chem 1:3909-3916
André S, Unverzagt C, Kojima S, Frank M, Seifert J, Fink C, Kayser K, von der Lieth CW, Gabius HJ (2004a) Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo. Eur J Biochem 271:118-134
Andre S, Kaltner H, Furuike T, Nishimura S, Gabius HJ (2004b) Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets. Bioconjug Chem 15:87-98
Bhat HK, Hacker HJ, Bannasch P, Thompson EA, Liehr JG (1993) Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm. Cancer Res 53:5447-5451
Bresalier RS, Yan PS, Byrd JC, Lotan R, Raz A (1997) Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system. Cancer 80:776-787
Brewer CF, Miceli MC, Baum LG (2002) Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions. Curr Opin Struct Biol 12:616-623
Brockhausen I, Schutzbach J, Kuhns W (1998) Glycoproteins and their relationship to human disease. Acta Anat (Basel) 161:36-78
Brohée R, Nonclercq D, Journé DN, Toubeau G, Falmagne P, Leclercq G, Heuson-Stiennon JA, Laurent G (2000) Demonstration of estrogen receptors and of estrogen responsiveness in the HKT-1097 cell line derived from diethylstilbestrol-induced kidney tumors. In Vitro Cell Dev Biol Anim 36:640-649
Bullock SL, Johnson TM, Bao Q, Hughes RC, Winyard PJ, Woolf AS (2001) Galectin-3 modulates ureteric bud branching in organ culture of the developing mouse kidney. J Am Soc Nephrol 12:515-523
Burger A, Filsinger S, Cooper DNW, Hansch GM (1996) Expression of the 14 kDa galactose binding protein, galectin-1 on human tubular epithelial cells. Kidney Int 50:754-759
Camby I, Belot N, Rorive S, Lefranc F, Maurage CA, Lahm H, et al (2001) Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration. Brain Pathol 11:12-26
Caselitz J (1987) Lectins and blood group substances as "tumor markers". Curr Top Pathol 77:245-277
Castronovo V, Liu FT, van den Brûle FA (1996) Decreased expression of galectin-3 in basal cell carcinoma of the skin. Int J Oncol 15:67-70
Choe YS, Shim C, Choi D, Sang Lee C, Lee KK, Kim K (1997) Expression of galectin-1 mRNA in the mouse uterus is under the control of ovarian steroids during blastocyst implantation. Mol Reprod Dev 48:261-266
Cooper DN (2002) Galectinomics: finding themes in complexity. Biochim Biophys Acta 1572:209-231
Cortes-Vizcaino V, Peydro-Olaya A, Llombart-Bosch A (1994) Morphological and immunohistochemical support for the interstitial cell origin of oestrogen-induced kidney tumors in the Syrian golden hamster. Carcinogenesis 15:2155-2162
Dagher SF, Wang JL, Patterson RJ (1995) Identification of galectin-3 as a factor in pre-mRNA splicing. Proc Natl Acad Sci U S A 92:1213-1217
Do Thi A, Jung-Testas I, Baulieu EE (1998) Neuronal signals are required for estrogen-mediated induction of progesterone receptor in cultured rat Schwann cells. J Steroid Biochem Mol Biol 67:201-211
Dodge AH, Brownfield M, Reid IA, Inagami T (1988) Immunohistochemical renin study of DES-induced renal tumor in the Syrian hamster. Am J Anat 182:347-352
Ekblom P, Nordling S, Saxen L, Rasilo ML, Renkonen O (1979) Cell interactions leading to kidney tubule determination are tunicamycin sensitive. Cell Differ 8:347-355
Foddy L, Stamatoglou SC, Hughes RC (1990) An endogenous carbohydrate-binding protein of baby hamster kidney (BHK21 C13) cells. Temporal changes in cellular expression in the developing kidney. J Cell Sci 97:139-148
Francois C, van Velthoven R, De Lathouwer O, Moreno C, Peltier A, Kaltner H, Salmon I, Gabius HJ, Danguy A, Decaestecker C, Kiss R (1999) Galectin-1 and galectin-3 binding pattern expression in renal cell carcinomas. Am J Clin Pathol 112:194-203
Gabius HJ (1988) Tumor lectinology: at the intersection of carbohydrate chemistry, biochemistry, cell biology and oncology. Angew Chem Int Ed Engl 27:1267-1276
Gabius HJ (1989) Potential participation of tumor lectins in cancer diagnosis, therapy and biology. Adv Lectin Res Z:87-106
Gabius HJ (1990) Influence of type of linkage and spacer on the interaction of beta-galactoside-binding proteins with immobilized affinity ligands. Anal Biochem 189:91-94
Gabius HJ (1997a) Concepts of tumor lectinology. Cancer Invest 15:454-464
Gabius HJ (2000) Biological information transfer beyond the genetic code: the sugar code. Naturwissenschaften 87:108-121
Gabius HJ (2001) Glycohistochemistry: the why and how of detection and localization of endogenous lectins. Anat Histol Embryol 30:3-31
Gabius HJ, Wosgien B, Hendrys M, Bardosi A (1991) Lectin localization in human nerve by biochemically defined lectin-binding glycoproteins, neoglycoprotein and lectin-specific antibody. Histochemistry 95:269-277
Gabius HJ, André S, Kaltner H, Siebert HC (2002) The sugar code: functional lectinomics. Biochim Biophys Acta 1572:165-177
Gabius HJ, Siebert HC, André S, Jiménez-Barbero J, Rüdiger H (2004) Chemical biology of the sugar code. ChemBioChem 5:740-764
Gillenwater A, Xu XC, el-Naggar AK, Clayman GL, Lotan R (1996) Expression of galectins in head and neck squamous cell carcinoma. Head Neck 18:422-432
Goldfarb S, Pugh TD (1990) Morphology and anatomic localization of renal microneoplasms and proximal tubule dysplasia induced by four different estrogens in the hamster. Cancer Res 50:113-119
Gonzalez A, Oberley TD, Li JJ (1989) Morphological and immunohistochemical studies of the estrogen-induced Syrian hamster renal tumor: probable cell of origin. Cancer Res 49:1020-1028
Hacker HJ, Bannasch P, Liehr J (1988) Histochemical analysis of the development of estradiol-induced kidney tumors in male Syrian hamsters. Cancer Res 48:971-976
He L, Andre S, Siebert HC, Helmholz H, Niemeyer B, Gabius HJ (2003) Detection of ligand- and solvent-induced shape alterations of cell-growth-regulatory human lectin galectin-1 in solution by small angle neutron and X-ray scattering. Biophys J 85:511-524
Hikita C, Vijayakumar S, Takito J, Erdjument-Bromage H, Tempst P, Al-Awqati Q (2000) Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3. J Cell Biol 151:1235-1246
Hittelet A, Camby I, Nagy N, Legendre H, Bronckart Y, Decaestecker C, Kaltner H, Nifant'ev NE, Bovin NV, Pector JC, Salmon I, Gabius HJ, Yeaton P (2003) Binding sites for Lewis antigens are expressed by human colon cancer cells and negatively affect their migration. Lab Invest 83:777-787
Holthofer H (1988) Cell type-specific glycoconjugates of collecting duct cells during maturation of the rat kidney. Cell Tissue Res 253:305-309
Honjo Y, Inohara H, Akahani S, Yoshii T, Takenaba Y, Yoshida J, Hattori K, Tomiyama Y, Raz A, Kubo T (2000) Expression of cytoplasmic galectin-3 as a prognostic marker in tongue carcinoma. Clin Cancer Res 6:4635-4640
Horning ES, Wittick JW (1954) The histogenesis of stilboestrol-induced renal tumors in the male golden hamster. Br J Cancer 8:541-547
Hsu DK, Dowling CA, Jeng KC, Chen JT, Yang RY, Liu FT (1999) Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma. Int J Cancer 81:519-526
Inohara H, Honjo Y, Yoshii T, Akahani S, Yoshida J, Hattori K, Okamoto S, Sawada T, Raz A, Kubo T (1999) Expression of galectin-3 in fine-needle aspirates as a diagnostic marker differentiating benign from malignant thyroid neoplasms. Cancer 85:2475-2484
Jung-Testas I, Schumacher M, Robel P, Baulieu EE (1994) Actions of steroid hormones and growth factors on glial cells of the central and peripheral nervous system. J Steroid Biochem Mol Biol 48:145-154
Kaltner H, Stierstorfer B (1998) Animal lectins as cell adhesion molecules. Acta Anat (Basel) 161:162-179
Kaltner H, Seyrek K, Heck A, Sinowatz F, Gabius HJ (2002) Galectin-1 and galectin-3 in fetal development of bovine respiratory and digestive tracts. Comparison of cell type-specific expression profiles and subcellular localization. Cell Tissue Res 307:35-46
Kirkman H, Bacon RL (1950) Malignant renal tumors in male hamsters (Cricetus auratus) treated with estrogen. Cancer Res 10:122-124
Kopitz J, von Reitzenstein C, Andre S, Kaltner H, Uhl J, Ehemann V, Cantz M, Gabius HJ (2001) Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3. J Biol Chem 276:35917-35923
Kopitz J, Andre S, von Reitzenstein C, Versluis K, Kaltner H, Pieters RJ, Wasano K, Kuwabara I, Liu FT, Cantz M, Heck AJ, Gabius HJ (2003) Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. Oncogene 22:6277-6288
Kriz W, Bankir L (1988) A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences (IUPS). Kidney Int 33:1-7
Lahm H, André S, Hoeflich A, Kaltner H, Siebert HC, Sordat B, von der Lieth CW, Wolf E, Gabius HJ (2004) Tumor galectinology: insights into the complex network of a family of endogenous lectins. Glycoconj J 20:227-238
Laitiner L, Virtanen I, Saxen L (1987) Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates. J Histochem Cytochem 35:55-65
Laurent G, Nonclercq D, Journé F, Brohée R, Toubeau G, Falmagne P, Heuson-Stiennon JA (1999) Characterization of a cell line established from diethylstilbestrol-induced renal tumors in Syrian hamsters. In Vitro Cell Dev Biol Anim 35:339-344
Li JJ, Li SA (1984) Estrogen-induced tumorigenesis in hamsters: roles for hormonal and carcinogenic activities. Arch Toxicol 55:110-118
Li JJ, Li SA (1990) Estrogen carcinogenesis in hamster tissues: a critical review. Endocr Rev 11:524-531
Li JJ, Weroha SJ, Davis MF, Tawfik O, Hou X, Li SA (2001) ER and PR in renomedullary interstitial cells during Syrian hamster estrogen-induced tumorigenesis: evidence for receptor-mediated oncogenesis. Endocrinology 142:4006-4014
Liehr JG (1997) Hormone-associated cancer: mechanistic similarities between human breast cancer and estrogen-induced kidney carcinogenesis in hamsters. Environ Health Perspect 105:565-569
Liehr JG (2001) Genotoxicity of the steroidal oestrogens oestrone and oestradiol: possible mechanism of uterine and mammary cancer development. Hum Reprod Update 7:273-281
Liehr JG, Fang WF, Sirbasku DA, Ari-Ulubelen A (1986) Carcinogenicity of catechol estrogens in Syrian hamsters. J Steroid Biochem 24:353-356
Liu FT, Patterson RJ, Wang JL (2002) Intracellular functions of galectins. Biochim Biophys Acta 1572:263-273
Llombart-Bosch A, Peydro A (1975) Morphological, histochemical and ultrastructural observations of diethylstilbestrol-induced kidney tumors in the Syrian golden hamster. Eur J Cancer 11:403-412
Lotan R, Belloni PN, Tressler RJ, Lotan D, Xu XC, Nicolson GL (1994) Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion. Glycoconj J 11:462-468
Lu J, Pei H, Kaeck M, Thompson HJ (1997) Gene expression changes associated with chemically induced rat mammary carcinogenesis. Mol Carcinog 20:204-215
Magnaldo T, Bernerd F, Darmon M (1995) Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid. Dev Biol 168:259-271
Matarrese P, Tinari N, Semeraro ML, Natoli C, Iacobelli S, Malorni W (2000) Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett 473:311-315
Morris S, Ahmad N, Andre S, Kaltner H, Gabius HJ, Brenowitz M, Brewer F (2004) Quaternary solution structures of galectins-1, -3, and -7. Glycobiology 14:293-300
Moutsatsos IK, Wade M, Schindler M, Wang JL (1987) Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts. Proc Natl Acad Sci U S A 84:6452-6456
Nagy N, Bronckart Y, Camby I, Legendre H, Phillipart P, Lahm H, et al (2002) Galectin-8 expression decreases in cancer as compared to normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration. Gut 50:392-401
Nagy N, Legendre H, Engels O, Andre S, Kaltner H, Wasano K, Zick Y, Pector JC, Decaestecker C, Gabius HJ, Salmon I, Kiss R (2003) Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting. Cancer 97:1849-1858
Nishiyama J, Kobayashi S, Ishida A, Nakabayashi I, Tajima O, Miura S, Katayama M, Nogami H (2000) Up-regulation of galectin-3 in acute renal failure of the rat. Am J Pathol 157:815-823
Nogueira E, Gardesa A, Mohr U (1993) Experimental models of kidney tumors. J Cancer Res Clin Oncol 119:190-198
Nonclercq D, Toubeau G, Wattiez R, Laurent G, Bernard A, Journe F, Falmagne P, Heuson-Stiennon JA (1998) Sublethal alterations and sustained cell proliferation associated with diethylstilbestrol-induced renal carcinogenesis in male Syrian golden hamsters. Eur J Morphol 36:83-96
Nonclercq D, Lienard V, Zanen J, Laurent G, Toubeau G (2002) Phenotypic variation and dynamic topography of transformed cells in an experimental model of diethylstilbestrol-induced renal tumor in male Syrian hamster. Histochem J 34:487-497
Nonclercq D, Journé F, Body JJ, Leclercq G, Laurent G (2004) Ligand-independent and agonist-mediated degradation of estrogen receptor α in breast carcinoma cells: evidence for distinct degradative pathways. Mol Cell Endocrinol 227:53-65
Oberley TD, Gonzalez A, Lauchner LJ, Oberley LW, Li JJ (1991) Characterization of early kidney lesions in estrogen-induced tumors in the Syrian hamster. Cancer Res 51:1922-1929
Rabinovich GA, Rubinstein N, Toscano MA (2002) Role of galectins in inflammatory and immunomodulatory processes. Biochim Biophys Acta 1572:274-284
Rappl G, Abken H, Muche JM, Sterry W, Tilgen W, Andre S, Kaltner H, Ugurel S, Gabius HJ, Reinhold U (2002) CD4+CD7- leukemic T cells from patients with Sezary syndrome are protected from galectin-1-triggered T cell death. Leukemia 16:840-845
Reuter G, Gabius HJ (1999) Eukaryotic glycosylation: whim of nature or multipurpose tool? Cell Mol Life Sci 55:368-422
Rorive S, Eddafali B, Fernandez S, Decaestecker C, Andre S, Kaltner H, Kuwabara I, Liu FT, Gabius HJ, Kiss R, Salmon I (2002) Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications. Mod Pathol 15:1294-1301
Rotblat B, Niv H, Andre S, Kaltner H, Gabius HJ, Kloog Y (2004) Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP. Cancer Res 64:3112-3118
Rüdiger H, Siebert HC, Solis D, Jimenez-Barbero J, Romero A, von der Lieth CW, Diaz-Marino T, Gabius HJ (2000) Medicinal chemistry based on the sugar code: fundamentals of lectinology and experimental strategies with lectins as targets. Curr Med Chem 7:389-416
Sanjuan X, Fernandez PL, Castells A, Castronovo V, van den Brule F, Liu FT, Cardesa A, Campo E (1997) Differential expression of galectin-3 and galectin-1 in colorectal cancer progression. Gastroenterology 113:1906-1915
Siebert HC, Andre S, Lu SY, Frank M, Kaltner H, van Kuik JA, Korchagina EY, Bovin N, Tajkhorshid E, Kaptein R, Vliegenthart JF, von der Lieth CW, Jimenez-Barbero J, Kopitz J, Gabius HJ (2003) Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins. Biochemistry 42:14762-14773
Takenaka Y, Fukumori T, Yoshii T, Oka N, Inohara H, Choi Kim HR, Bresalier RS, Raz A (2004) Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol Cell Biol 24:4395-4406
Toubeau G, Nonclercq D, Laurent G, Brohee R, Zanen J, Van Cauwenberge A, Alexandre H, Falmagne P, Heuson-Stiennon JA (2001) Immunohistochemical analysis of diethylstilbestrol induced renal tumors in adult male Syrian hamsters: evidence for relationship to peripheral nerve sheath tumors. Histochem Cell Biol 115:429-438
van den Brule FA, Berchuck A, Bast RC, Liu FT, Gillet C, Sobel ME, Castronovo V (1994) Differential expression of the 67-kD laminin receptor and 31-kD human laminin-binding protein in human ovarian carcinomas. Eur J Cancer 30A:1096-1099
van den Brule FA, Buicu C, Berchuck A, Bast RC, Deprez M, Liu FT, Cooper DN, Pieters C, Sobel ME, Castronovo V (1996) Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma. Hum Pathol 27:1185-1189
van den Brule FA, Waltregny D, Castronovo V (2001) Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients. J Pathol 193:80-87
van den Brule F, Califice S, Garnier F, Fernandez PL, Berchuck A, Castronovo V (2003) Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin. Lab Invest 83:377-386
Villalobo A, Gabius H (1998) Signaling pathways for transduction of the initial message of the glycocode into cellular responses. Acta Anat (Basel) 161:110-129
Vrasidas I, Andre S, Valentini P, Bock C, Lensch M, Kaltner H, Liskamp RM, Gabius HJ, Pieters RJ (2003) Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors. Org Biomol Chem 1:803-810
Wang L, Inohara H, Pienta KJ, Raz A (1995) Galectin-3 is a nuclear matrix protein which binds RNA. Biochem Biophys Res Commun 217:292-303
Wattiez R, Nonclercq D, Journe F, Toubeau G, Zanen J, Falmagne P, Heuson-Stiennon JA (1996) Involvement of transforming growth factor alpha and its receptor in a model of DES-induced renal carcinogenesis in the Syrian hamster. Carcinogenesis 17:1615-1622
Winyard PJ, Bao Q, Hughes RC, Woolf AS (1997) Epithelial galectin-3 during human nephrogenesis and childhood cystic diseases. J Am Soc Nephrol 8:1647-1657
Xu XC, el-Naggar AK, Lotan R (1995) Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications. Am J Pathol 147:815-822
Yager JD, Liehr JG (1996) Molecular mechanisms of estrogen carcinogenesis. Annu Rev Pharmacol Toxicol 36:203-232
Yang RY, Hsu DK, Liu FT (1996) Expression of galectin-3 modulates T-cell growth and apoptosis. Proc Natl Acad Sci U S A 93:6737-6742
