Profil

Laurent Guy


Main Research Fields
Immunology & infectious disease
Education & instruction
Oncology
Laboratory medicine & medical technology
Biochemistry, biophysics & molecular biology
Main Keywords
Nephrotoxicity; Aminoglycosides; Gentamicin; MIF; DES;
Main Co-authors
Heuson-Stiennon, Jeanine-Anne
Toubeau, Gérard
Nonclercq, Denis 
NONCLERCQ, Denis 
Tulkens, P.-M.

Publications (total 154)

The most downloaded
2 downloads
Journé, F., Durbecq, V., Chaboteaux, C., Rouas, G., Laurent, G., Nonclercq, D., Sotiriou, C., Body, J.-J., & Larsimont, D. (01 June 2009). Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients. Breast Cancer Research and Treatment, 115 (3), 523-535. doi:10.1007/s10549-008-0094-2 https://hdl.handle.net/20.500.12907/25731
The most cited
206 citations (Scopus®)
Laurent, G., Carlier, M.-B., Rollman, B., Van Hoof, F., & Tulkens, P.-M. (01 December 1982). Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin. Biochemical Pharmacology, 31 (23), 3861-3870. https://hdl.handle.net/20.500.12907/4775

Buxant, F., Kindt, N., Noel, J., Laurent, G., & Saussez, S. (16 March 2017). Preexposure of MCF-7 breast cancer cell line to dexamethasone alters the cytotoxic effect of paclitaxel but not 5-fluorouracil or epirubicin chemotherapy. Breast Cancer - Targets and Therapy, 9, 171-175.
Peer reviewed

Kindt, N., Journe, F., Laurent, G., & Saussez, S. (02 August 2016). Involvement of macrohage migration inhibitory factor in cancer and novel therapeutic targets (Review). Oncology Letters, 12, 2247-2253.
Peer Reviewed verified by ORBi

Buxant, F., Kindt, N., Laurent, G., Noel, J., & Saussez, S. (12 June 2015). Antiproliferative effect of dexamethasone in the MCF-7 breast cancer cell line. Molecular Medicine Reports, 12.
Peer Reviewed verified by ORBi

Kindt, N., Richard, V., Laurent, G., & Saussez, S. (22 May 2015). Implication du Macrophage migration Inhibitory Factor dans les cancers du sein. Poster session presented at Journée UMHAP, Mons, Belgium.

Vincent, R., Kindt, N., Decaestecker, C., Gabius, H.-J., Laurent, G., Noel, J., & Saussez, S. (16 August 2014). Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer. Oncology Reports, 32 (2), 523-529.
Peer Reviewed verified by ORBi

Richard, V., Kindt, N., Decaestecker, C., Gabius, H.-J., Laurent, G., Noel, J., & Saussez, S. (2014). Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer. Oncology Reports.
Peer Reviewed verified by ORBi

Kindt, N., Lechien, J., Nonclercq, D., Laurent, G., & Saussez, S. (11 June 2014). Involvement of CD74 in head and neck squamous cell carcinomas. Journal of Cancer Research and Clinical Oncology, 140 (6), 937-947.
Peer Reviewed verified by ORBi

Valentini, X., Laurent, G., & Nonclercq, D. (12 May 2013). Toxicity of TiO2 nanoparticles on NRK52 renal cell line. Paper presented at Colloque Nanohybrides, Porquerolles, France.

Lechien, J., Kindt, N., Costa, P., Preillon, J., Chantrain, G., Laurent, G., & Saussez, S. (01 April 2013). MIF in Head and Neck cancer: a new therapeutic target ? : Le MIF dans les cancers des voies aéro-digestives supérieures : une nouvelle thérapie ciblée ? Revue de Laryngologie - Otologie - Rhinologie, 134 (2), 67-74.
Peer Reviewed verified by ORBi

Arcolia, V., Rifaut, C., Remmelink, M., Laurent, G., & Saussez, S. (12 March 2013). Galectin -1: a new potential biomarker for thyroid cancers. Poster session presented at 7ème édition de la Matinée de Chercheurs, Mons, Belgium.

Valentini, X., Laurent, G., & Nonclercq, D. (12 March 2013). Toxicity of TiO2 nanoparticles on NRK52E renal cell line. Poster session presented at 7ième Matinée des Chercheurs, Mons, Belgium.

Journe, F., Wiedig, M., Monrandini, R., El Hajj, P., Krayem, M., Sales, F., Theunis, A., Larsimont, D., Absil, L., Laurent, G., Gilot, D., Galibert, M.-D., Awada, A., & Ghanem, G. (08 March 2013). Tyrosine-related protein 1 (TYRP1) expression correlates with markers of both differentiation/pigmentation and proliferation in melanoma. Poster session presented at Journée des doctorants, Bruxelles, Belgium.

Kindt, N., Preillon, J., Laurent, G., Gabius, H.-J., Decaestecker, C., Johnson, B., Chantrain, G., & Saussez, S. (14 February 2013). Involvement of Macrophage Migration Inhibitory Factor in Head and Neck Squamous Cell Carcinoma. Poster session presented at 1st Symposium of Cancer Research Center of Lyon, Lyon, France.

Richard, V., Conotte, R., Kindt, N., Faverly, D., Laurent, G., Colet, J.-M., Noël, J. C., & Saussez, S. (29 January 2013). INTEGRATING PROTEOMICS AND METABONOMICS FOR A BETTER UNDERSTANDING OF HUMAN BREAST CANCER BIOLOGY. Poster session presented at 1ère journée des doctorants en Sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Arcolia, V., Rifaut, C., Remmelink, M., Laurent, G., & Saussez, S. (29 January 2013). Galectin -1: a new potential biomarker for thyroid cancers. Poster session presented at 1ère journée des doctorants en Sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Valentini, X., Laurent, G., & Nonclercq, D. (29 January 2013). Toxicity of TiO2 nanoparticles on NRK52E renal cell line. Poster session presented at ', Journée de l'école doctorale en sciences biomédicales et pharmaceutiques, UMONS, Mons, Belgium.

Kindt, N., Lechien, J., Journé, F., Ghanem, G., Duvillier, H., Laurent, G., & Saussez, S. (29 January 2013). Involvement of CD74 in head and neck squamous cell carcinoma. Paper presented at 1ère journée des doctorants en Sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Kindt, N., Preillon, J., Kaltner, H., Gabius, H.-J., Chevalier, D., Rodriguez, A., Johnson, B., Megalizzi, V., Decaestecker, C., Laurent, G., & Saussez, S. (25 January 2013). Macrophage migration inhibitory factor in head and neck squamous cell carcinoma: clinical and experimental studies. Journal of Cancer Research and Clinical Oncology, 139 (5), 727-737.
Peer Reviewed verified by ORBi

Kindt, N., Laurent, G., Nonclercq, D., Journé, F., Ghanem, G., Duvillier, H., Gabius, H.-J., Lechien, J., & Saussez, S. (12 January 2013). Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells. International Journal of Oncology, 43 (1), 185-193.
Peer Reviewed verified by ORBi

Kindt, N., Lechien, J., Decaestecker, C., Rodriguez, A., Chantrain, G., Remmelink, M., Laurent, G., Gabius, H.-J., & Saussez, S. (12 October 2012). Expression of Macrophage Migration-Inhibitory Factor is Correlated with Progression in Oral Cavity Carcinomas. Anticancer Research, 32 (10), 4499-4506.
Peer Reviewed verified by ORBi

Journé, F., Id Boufker, H., Van Kempen, L., Galibert, M.-D., Wiedig, M., Salès, F., Theunis, A., Nonclercq, D., Frau, A., Laurent, G., Awada, A., & Ghanem, G. (22 November 2011). TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome. British Journal of Cancer, 105 (11), 1726-1732.
Peer Reviewed verified by ORBi

Id Boufker, H., Lagneaux, L., Fayyad-Kazan, H., Badran, B., Najar, M., Wiedig, M., Ghanem, G., Laurent, G., Body, J.-J., & Journé, F. (26 August 2011). Role of farnesoid X receptor (FXR) in the process of differentiation of bone marrow stromal cells into osteoblasts. BONE, 49, 1219-1231.
Peer Reviewed verified by ORBi

Leclercq, G., Gallo, D., Cossy, J., Laïos, I., Larsimont, D., Laurent, G., & Jacquot, Y. (01 August 2011). Peptides targeting estrogen receptor alpha - Potential applications for breast cancer treatment. Current Pharmaceutical Design, 17 (25), 2632-2653.
Peer Reviewed verified by ORBi

Journé, F., Id Boufker, H., Van Kempen, L., Galibert, M.-D., Wiedig, M., Theunis, A., Salès, F., Nonclercq, D., Frau, A., Laurent, G., Awada, A., & Ghanem, G. (04 September 2010). Gene expression profiling and RTqPCR validation in 133 melanoma metastases identify TYRP1 mRNA level as a new prognosis marker in high risk melanoma. Paper presented at 16th Meeting of the European Society for Pigment Cell Research, Hinxton, Cambridge, United Kingdom.

Bourgoin-Voillard, S., Gallo, D., Laïos, I., Cleeren, A., El Bali, L., Jacquot, Y., Nonclercq, D., Laurent, G., Tabet, J.-C., & Leclercq, G. (01 March 2010). Capacity of type I and II ligands to confer to estrogen receptor alpha an appropriate conformation for the recruitment of coactivators containing a LxxLL motif - Relationship with the regulation of receptor level and ERE-dependent transcription in MCF-7 c. Biochemical Pharmacology, 79 (5), 746-757. doi:10.1016/j.bcp.2009.10.015
Peer Reviewed verified by ORBi

Journé, F., Id Boufker, H., Wiedig, M., Salès, F., Theunis, A., Nonclercq, D., Frau, A., Laurent, G., Awada, A., & Ghanem, G. (29 October 2009). Gene expression profiling identifies the pigmentation-related gene TYRP1 in poor prognosis high risk melanoma. Paper presented at EORTC Melanoma Group Meeting, St Jamese's University Hospital, Leeds, United Kingdom.

Journé, F., Durbecq, V., Chaboteaux, C., Rouas, G., Laurent, G., Nonclercq, D., Sotiriou, C., Body, J.-J., & Larsimont, D. (01 June 2009). Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients. Breast Cancer Research and Treatment, 115 (3), 523-535. doi:10.1007/s10549-008-0094-2
Peer Reviewed verified by ORBi

Agouridas, V., Magnier, E., Blazejewski, J.-C., Laïos, I., Cleeren, A., Nonclercq, D., Laurent, G., & Leclercq, G. (12 February 2009). Effect of fluorination on the pharmacological profile of 11beta isomers of fulvestrant in breast carcinoma cells. Journal of Medicinal Chemistry, 52 (3), 883-887. doi:10.1021/jm801154q
Peer Reviewed verified by ORBi

Gallo, D., Jacquot, Y., Laurent, G., & Leclercq, G. (01 October 2008). Calmodulin : a regulatory partner of the estrogen receptor alpha in breast cancer cells. Molecular and Cellular Endocrinology, 291 (1), 20-26. doi:10.1016/j.mce.2008.04.011
Peer Reviewed verified by ORBi

Journé, F., Body, J.-J., Leclercq, G., & Laurent, G. (01 May 2008). Hormone therapy for breast cancer, with an emphasis on the pure antiestrogen fulvestrant : mode of action, antitumor efficacy and effects on bone health. Expert Opinion on Drug Safety, 7 (3), 241-258. doi:10.1517/14740338.7.3.241
Peer Reviewed verified by ORBi

Gallo, D., Haddad, I., Laurent, G., Vinh, J., Jacquemotte, F., Jacquot, Y., & Leclercq, G. (01 April 2008). Regulatory function of the P295-T311 motif of the estrogen receptor a - does proteasomal degradation induce emergence of peptides implicated in estrogenic responses? Nuclear Receptor Signaling, 6, 007. doi:10.1621/nrs.06007
Peer reviewed

Gallo, D., Haddad, I., Duvillier, H., Jacquemotte, F., Laïos, I., Laurent, G., Jacquot, Y., Vinh, J., & Leclercq, G. (01 March 2008). Trophic effect in MCF-7 cells of ERa17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor a - Underlying mechanisms. Journal of Steroid Biochemistry and Molecular Biology, 109 (1), 138-149. doi:10.1016/j.jsbmb.2007.12.012
Peer Reviewed verified by ORBi

Journé, F., Kheddoumi, N., Chaboteaux, C., Duvillier, H., Laurent, G., & Body, J.-J. (01 January 2008). Extracellular calcium increases bisphosphonate-induced growth inhibition of breast cancer cells. Breast Cancer Research, 10 (1), 4. doi:10.1186/bcr1845
Peer Reviewed verified by ORBi

Journé, F., Laurent, G., Chaboteaux, C., Nonclercq, D., Durbecq, V., Larsimont, D., & Body, J.-J. (01 January 2008). Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. Breast Cancer Research and Treatment, 107 (1), 49-61. doi:10.1007/s10549-007-9535-6
Peer Reviewed verified by ORBi

Saussez, S., Glinoer, D., Chantrain, G., Pattou, F., Carnaille, B., André, S., Gabius, H.-J., & Laurent, G. (01 January 2008). Serum galectin-1 and galectin-3 levels in benign and malignant thyroid nodular disease. Thyroid, 18 (7), 705-712.
Peer Reviewed verified by ORBi

Saussez, S., Lorfevre, F., Lequeux, T., Laurent, G., Chantrain, G., Vertongen, F., Toubeau, G., Decaestecker, C., & Kiss, R. (01 January 2008). The Determination of the Levels of Circulating Galectin-1 and -3 in HNSCC Patients Could Be Used to Monitor Tumor Progression and/or Responses to Therapy. Oral Oncology, 44, 86-93.
Peer Reviewed verified by ORBi

Laïos, I., Cleeren, A., Leclercq, G., Nonclercq, D., Laurent, G., Schlenk, M., Wellner, A., & Gust, R. (01 October 2007). Effects of (R,S)/(S,R)-4,5-bis(2-chloro-4-hydroxyphenyl)-2-imidazolines and (R,S)/(S,R)-2,3-bis(2-chloro-4-hydroxyphenyl)piperazines on ER alpha levels and transcriptional activity in MCF-7 cells. Biochemical Pharmacology, 74 (7), 1029-1038. doi:10.1016/j.bcp.2007.06.045
Peer Reviewed verified by ORBi

Nonclercq, D., Journé, F., Laïos, I., Chaboteaux, C., Toillon, R.-A., Leclercq, G., & Laurent, G. (01 August 2007). Effect of nuclear export inhibition on estrogen receptor regulation in breast cancer cells. Journal of Molecular Endocrinology, 39 (2), 105-118. doi:10.1677/JME-07-0040
Peer Reviewed verified by ORBi

Gallo, D., Jacquot, Y., Cleeren, A., Jacquemotte, F., Laïos, I., Laurent, G., & Leclercq, G. (01 July 2007). Molecular basis of agonistic activity of ERa17p, a synthetic peptide corresponding to a sequence located at the N-terminal part of the estrogen receptor a ligand binding domain. Letters in Drug Design and Discovery, 4 (5), 346-355. doi:10.2174/157018007780867807
Peer Reviewed verified by ORBi

Journé, F., Laurent, G., Chaboteaux, C., Nonclercq, D., Durbecq, V., Larsimont, D., & Body, J.-J. (15 May 2007). Bone-derived lipids stimulates breast cancer cell growth through a cross-talk between farnesoid X receptor and estrogen receptor : in vitro and clinica data. Paper presented at 34th European Symposium on Calcified Tissues, Copenhagen, Denmark.

Gallo, D., Jacquemotte, F., Cleeren, A., Laïos, I., Hadiy, S., Rowlands, M. G., Caille, O., Nonclercq, D., Laurent, G., Jacquot, Y., & Leclercq, G. (01 March 2007). Calmodulin-independent, agonistic properties of a peptide containing the calmodulin binding site of estrogen receptor alpha. Molecular and Cellular Endocrinology, 268 (1), 37-49. doi:10.1016/j.mce.2007.01.012
Peer Reviewed verified by ORBi

Jacquot, Y., Laïos, I., Cleeren, A., Nonclercq, D., Bermont, L., Refouvelet, B., Boubekeur, K., Xicluna, A., Leclercq, G., & Laurent, G. (01 March 2007). Synthesis, structure and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells. Bioorganic and Medicinal Chemistry, 15 (6), 2269-2282. doi:10.1016/j.bmc.2007.01.025
Peer Reviewed verified by ORBi

Journé, F., Laurent, G., Chaboteaux, C., Nonclercq, D., Durbecq, V., Larsimont, D., & Body, J.-J. (09 January 2007). Bone-derived lipid stimulates breast cancer cell growth through crosstalk between farnesoid X receptor and estrogen receptor. Paper presented at Annual Meeting of the Belgian Association for Cancer Research, Ghent, Belgium.

Journé, F., Laurent, G., Durbecq, V., Chaboteaux, C., Nonclercq, D., Larsimont, D., & Body, J.-J. (14 December 2006). Farnesoid X receptor : a new marker of poor prognosis in luminal subtype of breast carcinomas? Paper presented at 29th Annual San Antonio Breast Cancer Symposium, San Antonio, United States - Texas.

Journé, F., Laurent, G., Durbecq, V., Chaboteaux, C., Nonclercq, D., Larsimont, D., & Body, J.-J. (10 December 2006). Crosstalk between farnesoid X receptor and estrogen receptor might account for mitogenic effect of bone-derived lipids in bone metastasis from breast cancer. Paper presented at VI International Meeting on Cancer Induced Bone Disease, Cancer and Bone Society, San Antonio, United States - Texas.

Journé, F., Chaboteaux, C., Magne, N., Duvillier, H., Laurent, G., & Body, J.-J. (01 December 2006). Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines. Breast Cancer Research, 8 (1), 2. doi:10.1186/bcr1363
Peer Reviewed verified by ORBi

Journé, F., Laurent, G., Chaboteaux, C., Nonclercq, D., Larsimont, D., & Body, J.-J. (15 September 2006). Bone-derived lipid stimulates MCF-7 breast cancer cell growth through farnesoid X receptor-mediated estrogen receptor activation. Paper presented at Twenty-Eighth Annual Meeting of American Society for Bone and Mineral Research, Philadelphia, United States - Pennsylvania.

Saussez, S., Lorfèvre, F., Nonclercq, D., Laurent, G., André, S., Journé, F., Kiss, R., Toubeau, G., & Gabius, H.-J. (01 July 2006). Towards functional glycomics by localization of binding sites for tissue lectins : lectin histochemical reactivity for galectins during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. Histochemistry and Cell Biology, 126 (1), 57-69. doi:10.1007/s00418-006-0146-9
Peer Reviewed verified by ORBi

Debauve, G., Nonclercq, D., Ribaucour, F., Wiedig, M., Gerbaux, C., Leo, O., Laurent, G., Journé, F., Belayew, A., & Toubeau, G. (08 June 2006). Early expression of the Helicase-Like Transcription Factor (HLTF/SMARCA3) in an experimental model of estrogen-induced renal carcinogenesis. Molecular Cancer, 5, 23-34. doi:10.1186/1476-4598-5-23
Peer reviewed

Leclercq, G., Lacroix, M., Laïos, I., & Laurent, G. (01 February 2006). Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells. Current Cancer Drug Targets, 6 (1), 39-64.
Peer Reviewed verified by ORBi

Journé, F., Chaboteaux, C., Nonclercq, D., Leclercq, G., Laurent, G., & Body, J.-J. (11 January 2006). Farnesol, an intermediate of the mevalonate pathway, stimulates breast cancer cell growth through the activation of estrogen receptor. Paper presented at Annual Meeting of the Belgian Association for Cancer Research, Antwerpen, Belgium.

Laïos, I., Journé, F., Nonclercq, D., Salazar Vidal, D., Toillon, R.-A., Laurent, G., & Leclercq, G. (01 March 2005). Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells. Journal of Steroid Biochemistry and Molecular Biology, 94 (4), 347-359. doi:10.1016/j.jsbmb.2005.02.005
Peer Reviewed verified by ORBi

Saussez, S., Nonclerq, D., Laurent, G., Wattiez, R., André, S., Kaltner, H., Gabius, H.-J., Kiss, R., & Toubeau, G. (01 January 2005). Towards functional glycomics by localization of tissue lectins: immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. Histochemistry and Cell Biology, 123 (1), 29-41. doi:10.1007/s00418-004-0733-6
Peer Reviewed verified by ORBi

Nonclercq, D., Journé, F., Body, J.-J., Leclercq, G., & Laurent, G. (30 November 2004). Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells : evidence for distinct degradative pathways. Molecular and Cellular Endocrinology, 227 (1-2), 53-65. doi:10.1016/j.mce.2004.07.003
Peer Reviewed verified by ORBi

Journé, F., Chaboteaux, C., Dumon, J.-C., Leclercq, G., Laurent, G., & Body, J.-J. (01 November 2004). Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells. British Journal of Cancer, 91 (9), 1703-1710.
Peer Reviewed verified by ORBi

Saussez, S., Nonclercq, D., Laurent, G., Wattiez, R., André, S., Kaltner, H., Gabius, H.-J., Kiss, R., & Toubeau, G. (21 October 2004). Toward functional glycomics by localization of tissue lectins : immunohistochemical galectin fingerprinting during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster. Histochemistry and Cell Biology, 123, 29-41.
Peer Reviewed verified by ORBi

Journé, F., Body, J.-J., Leclercq, G., Nonclercq, D., & Laurent, G. (01 July 2004). Estrogen responsiveness of IBEP-2, a new human cell line derived from breast carcinoma. Breast Cancer Research and Treatment, 86 (1), 39-53. doi:10.1023/B:BREA.0000032922.87541.31
Peer Reviewed verified by ORBi

Laïos, I., Journé, F., Laurent, G., Nonclercq, D., Toillon, R.-A., Seo, H. S., & Leclercq, G. (01 November 2003). Mechanisms governing the accumulation of estrogen receptor alpha in MCF-7 breast cancer cells treated with hydroxytamoxifen and related antiestrogens. Journal of Steroid Biochemistry and Molecular Biology, 87 (2-3), 207-221.
Peer Reviewed verified by ORBi

Genlain, M., Nonclercq, D., Laurent, G., Toubeau, G., Godaux, E., & Ris, L. (20 February 2003). Properties of neurons from the rat medial vestibular nucleus in microexplant culture. Neuroscience Letters, 338 (1), 45-48.
Peer Reviewed verified by ORBi

Blazejewski, J.-C., Wilmshurst, M. P., Popkin, M. D., Wakselman, C., Laurent, G., Nonclercq, D., & Cleren, A. (06 February 2003). Synthesis, characterization and biological evaluation of 7 alpha-perfluoroalkylestradiol derivatives. Bioorganic and Medicinal Chemistry, 11 (3), 335-345.
Peer Reviewed verified by ORBi

Nonclercq, D., Liénard, V., Zanen, J., Laurent, G., & Toubeau, G. (01 October 2002). Phenotypic variations and dynamic topography of transformed cells in an experimental model of diethylstilbestrol-induced renal tumour in male Syrian hamster. Histochemical Journal, 34 (10), 487-497.
Peer Reviewed verified by ORBi

Toubeau, G., Nonclercq, D., Laurent, G., Brohée, R., Zanen, J., Van Cauwenberge, A., & Heuson-Stiennon, J.-A. (01 May 2001). Immunohistochemical analysis of diethylstilbestrol-induced renal tumors in adult male Syrian hamsters: evidence for relationship to peripheral nerve sheath tumors. Histochemistry and Cell Biology, 115 (5), 429-438.
Peer Reviewed verified by ORBi

Van Cauwenberge, A., Nonclercq, D., Laurent, G., Zanen, J., Beckers, J.-F., Heuson-Stiennon, J.-A., & Toubeau, G. (01 February 2001). Immunohistochemistry of the golden hamster pituitary during chronic administration of diethylstilbestrol: a quantitative analysis using confocal laser scanning microscopy. Histochemistry and Cell Biology, 115 (2), 169-178.
Peer Reviewed verified by ORBi

Brohée, R., Nonclercq, D., Journé, F., Toubeau, G., Falmagne, P., Leclercq, G., Heuson-Stiennon, J.-A., & Laurent, G. (01 November 2000). Demonstration of estrogen receptors and of estrogen responsiveness in the HKT-1097 cell line derived from diethylstilbestrol-induced kidney tumors. In Vitro Cellular and Developmental Biology. Animal, 36 (10), 640-649.
Peer Reviewed verified by ORBi

El Mouedden, M., Laurent, G., Mingeot-Leclercq, M.-P., & Tulkens, P.-M. (01 July 2000). Gentamicin-induced apoptosis in renal cell lines and embryonic rat fibroblasts. Toxicological Sciences, 56 (1), 229-239.

El Mouedden, M., Laurent, G., Mingeot-Leclercq, M.-P., Taper, H.-S., Cumps, J., & Tulkens, P.-M. (01 March 2000). Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides. Antimicrobial Agents and Chemotherapy, 44 (3), 665-675.
Peer Reviewed verified by ORBi

Laurent, G., Nonclercq, D., Journé, F., Brohée, R., Toubeau, G., Falmagne, P., & Heuson-Stiennon, J.-A. (01 June 1999). Characterization of a cell line established from diethylstilbestrol-induced renal tumors in Syrian hamsters. In Vitro Cellular and Developmental Biology. Animal, 35 (6), 339-345.
Peer Reviewed verified by ORBi

Brohée, R., Laurent, G., Nonclercq, D., Falmagne, P., & Heuson-Stiennon, J.-A. (1999). Implication of erbB-2 and erbB-3 receptor tyrosine kinase pathway in a model of estrogen-induced carcinogenesis. Paper presented at Société Belge de Biochimie et de Biologie Moléculaire, Namur, Belgium.

Nonclercq, D., Zanen, J., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (01 February 1999). Apoptosis and cell proliferation in the seminal vesicles and coagulating glands of male Syrian hamsters exposed to diethylstilboestrol (DES). Reproduction, Fertility and Development, 11 (2), 111-122.
Peer Reviewed verified by ORBi

Nonclercq, D., Zanen, J., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (1999). Diethylstilbestrol-induced apoptosis and cell proliferation in male hamster accessory sex glands. Paper presented at Réunion de la Société Belge de Biologie Cellulaire, Gent , Belgium.

Nonclercq, D., Toubeau, G., Wattiez, R., Laurent, G., Bernard, A., Journé, F., Falmagne, P., & Heuson-Stiennon, J.-A. (01 April 1998). Sublethal alterations and sustained cell proliferation associated with the diethylstilbestrol-induced renal carcinogenesis in male Syrian golden hamsters. European Journal of Morphology, 36 (2), 83-96.
Peer Reviewed verified by ORBi

Piron, A., Leonard, I., Nonclercq, D., Toubeau, G., Falmagne, P., Heuson-Stiennon, J.-A., & Laurent, G. (01 February 1998). In vitro demonstration of a mitogenic activity in renal tissue extracts during regenerative hyperplasia. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology, 274 (2Pt2), 348-357.
Peer Reviewed verified by ORBi

Journé, F., Brohée, R., Wattiez, R., Nonclercq, D., Toubeau, G., Laurent, G., Zanen, J., Heuson-Stiennon, J.-A., & Falmagne, P. (07 October 1997). Transforming growth factor alpha (TGFalpha) receptor regulation in kidney tissue of diethylstilbestrol (DES) treated hamster. Paper presented at Invasion and Metastasis, International Institute of Cancer Research, Athènes, Greece.

Journé, F., Wattiez, R., Piron, A., Carion, M., Laurent, G., Heuson-Stiennon, J.-A., & Falmagne, P. (05 May 1997). Renal epidermal growth factor precursor: proteolytic processing in an in vitro cell-free system. BBA Molecular Cell Research, 1357 (1), 18-30.
Peer Reviewed verified by ORBi

Beauchamp, D., Laurent, G., Grenier, L., Gourde, P., Zanen, J., Heuson-Stiennon, J.-A., & Bergeron, M. (01 May 1997). Attenuation of gentamicin-induced nephrotoxicity in rats by fleroxacin. Antimicrobial Agents and Chemotherapy, 41 (6), 1237-1245.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Servais, D., Journé, F., Wattiez, R., Laurent, G., Zanen, J., Falmagne, P., & Heuson-Stiennon, J.-A. (06 February 1997). Etude de l'apoptose et de la prolifération cellulaire dans un modèle expérimental de cancérogenèse rénale chez le hamster mâle. Paper presented at 3ème Forum Télévie, ULB Erasme, Belgium.

Nonclercq, D., Reverse, D., Toubeau, G., Laurent, G., Zanen, J., & Heuson-Stiennon, J.-A. (1996). In situ demonstration of apoptotic germ cells in an experimental model of chemical castration. In Biochemicals Boehringer Mannheim. Boehringer Mannheim.

Nonclercq, D., Reverse, D., Toubeau, G., Beckers, J.-F., Sulon, J., Laurent, G., Zanen, J., & Heuson-Stiennon, J.-A. (01 December 1996). In situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male Syrian hamsters. Biology of Reproduction, 55 (6), 1368-1376.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Servais, D., Journé, F., Wattiez, R., Laurent, G., Zanen, J., Falmagne, P., & Heuson-Stiennon, J.-A. (1996). Apoptosis and cell proliferation in a model of renal tumor in the male Syrian hamster exposed to diethylstilbestrol. Paper presented at SBCF Euroconference Meeting on 'Cell proliferation and Tumor Suppressors', Montpellier, France.

Nonclercq, D., Toubeau, G., Wattiez, R., Laurent, G., Bernard, A., Journé, F., Falmagne, P., & Heuson-Stiennon, J.-A. (02 July 1996). Potential involvement of a alpha2U-globulin-like protein in an experimental model of hormonal kidney carcino-genesis in the Syrian golden hamster. Paper presented at XIII th International Congress of Nephrology, International Society of Nephrology (I.S.N), Madrid, Spain.

Nonclercq, D., Reverse, D., Toubeau, G., Laurent, G., Zanen, J., & Heuson-Stiennon, J.-A. (1995). Apoptosis and cell proliferation in seminiferous epithelium : an immunocytochemical study of diethylstilbetrol-treated male hamster. Paper presented at 36ème Réunion de la Société Belge de Biologie Cellulaire, Mons, Belgium.

Piron, A., Léonard, I., Wattiez, R., Falmagne, P., Toubeau, G., Nonclercq, D., Laurent, G., & Heuson-Stiennon, J.-A. (1995). Increase of soluble epidermal growth factor and appearance of a mitogenic activity in renal tissue extracts during nephrogenic repair. Paper presented at 29th Annual Meeting of the European Society for Clinical Investigation and the Medical Society of Great Britain, Cambridge, United Kingdom.

Wattiez, R., Journé, F., Piron, A., Toubeau, G., Nonclercq, D., Laurent, G., Heuson-Stiennon, J.-A., & Falmagne, P. (1995). Enzymatic processing of the epidermal growth factor precursor in rat renal tissue : an in vitro study. Paper presented at 29th Annual Meeting of the European Society for Clinical Investigation and the Medical Society of Great Britain, Cambridge, United Kingdom.

Nonclercq, D., Toubeau, G., Wattiez, R., Bernard, A., Laurent, G., Journé, F., Falmagne, P., & Heuson-Stiennon, J.-A. (16 February 1995). Prolifération cellulaire et thésaurismose lysosomiale dans un modèle expérimental de cancérogenèse rénale chez le hamster. Paper presented at 1er Forum Télévie, Université de Liège, Belgium.

Toubeau, G., Nonclercq, D., Zanen, J., Laurent, G., Schaudies, P., & Heuson-Stiennon, J.-A. (01 July 1994). Renal tissue expression of EGF and EGF receptor after ischaemic tubular injury: an immunohistochemical study. Experimental Nephrology, 2 (4), 229-239.
Peer Reviewed verified by ORBi

Morin, N., Frau, A., Nonclercq, D., Toubeau, G., Zanen, J., Heuson-Stiennon, J.-A., Bergeron, M., Beauchamp, D., & Laurent, G. (01 June 1994). Potentiation of gentamicin nephrotoxicity in the rat by infusion of aprotinin. Experimental and Molecular Pathology, 60 (3), 197-213.
Peer Reviewed verified by ORBi

Zanen, J., Carinci, V., Nonclercq, D., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (1994). Computer assisted morphometry and 3D reconstruction of cystic tubules in rat kidney after exposure to cisplatin. Paper presented at Third Conference ot the European Society for Analytical Cellular Pathology, Grenoble, France.

Leonard, I., Zanen, J., Nonclercq, D., Toubeau, G., Heuson-Stiennon, J.-A., Beckers, J.-F., Falmagne, P., Schaudies, R., & Laurent, G. (01 May 1994). Modification of immunoreactive EGF and EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin. Renal Failure, 16 (5), 583-608.
Peer Reviewed verified by ORBi

Léonard, I., Beckers, J.-F., Zanen, J., Nonclercq, D., Toubeau, G., Heuson-Stiennon, J.-A., Schaudies, P., Laurent, G., & Falmagne, P. (1993). Modification of epidermal growth factor (EGF) level in rat kidney tissue after tubular necrosis induced by tobramycin or cisplatin. Paper presented at Société Belge de Biochimie, UCL, Belgium.

Zanen, J., Carinci, V., Nonclercq, D., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (08 November 1993). Morphometric and tridimensional studies of tubular cystic degeneration in rat kidney following exposure to ciplatin. Analytical Cellular Pathology, 5, 353-366.
Peer Reviewed verified by ORBi

Toubeau, G., Nonclercq, D., De Moor, S., Laurent, G., Schaudies, P., & Heuson-Stiennon, J.-A. (01 September 1993). Immunocytological demonstration of EGF, EGF receptor and vimentin in the kidney during acute tubular necrosis and tubular regeneration. Paper presented at Immunocytochemistry and allied techniques. Joint meeting of the Royal Microscopical Society and the Belgian Societies, Bruxelles, Belgium.

Schaudies, R., Nonclercq, D., Nelson, L., Toubeau, G., Heuson-Stiennon, J.-A., & Laurent, G. (01 September 1993). Endogenous EGF as a potential renotrophic factor in ischemia-induced acute renal failure. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology, 265 (3), 425-434.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Laurent, G., Schaudies, R., Zanen, J., & Heuson-Stiennon, J.-A. (30 August 1993). Immunocytological localization of epidermal growth factor in the rat kidney after drug-induced tubular injury. European Journal of Morphology, 31, 65-71.
Peer Reviewed verified by ORBi

Nonclercq, D., Wrona, S., Toubeau, G., Zanen, J., Heuson-Stiennon, J.-A., Schaudies, R., & Laurent, G. (18 August 1993). Immunohistochemical study of epidermal growth factor in the rat kidney after gentamicin-induced tubular injury. Contributions to Nephrology, 101, 206-212.
Peer Reviewed verified by ORBi

Schaudies, R., Nonclercq, D., Nelson, L., Toubeau, G., Heuson-Stiennon, J.-A., & Laurent, G. (1992). Endogenous EGF as a potential renotrophic factor in ischemia induced acute renal failure. Paper presented at 25th Annual Meeting of the American Society of Nephrology, Baltimore, United States - Maryland.

Morin, N., Laurent, G., Nonclercq, D., Toubeau, G., Heuson-Stiennon, J.-A., Bergeron, M., & Beauchamp, D. (11 October 1992). Epidermal growth factor (EGF) accelerates renal tissue repair in a rat model of gentamicin (G) nephrotoxicity. Paper presented at 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy, Anaheim (Californie), United States - California.

Morin, N., Laurent, G., Frau, A., Nonclercq, D., Toubeau, G., Heuson-Stiennon, J.-A., Bergeron, M., & Beauchamp, D. (08 October 1992). Rôle de l'EGF dans la régénération tubulaire rénale après traitement à la gentamycine : effet de l'aprotinine. Paper presented at Club de recherches cliniques du Québec : 34ème réunion annuelle, Montebello, Canada.

Kishore, B. K., Ibrahim, S., Lambricht, P., Laurent, G., Maldague, P., & Tulkens, P.-M. (01 July 1992). Comparative assessment of poly-L-aspartic and poly-L-glutamic acids as protectants against gentamicin-induced renal lysosomal phospholipidosis, phospholipiduria and cell proliferation in rats. Journal of Pharmacology and Experimental Therapeutics, 262 (1), 424-432.
Peer Reviewed verified by ORBi

Morin, N., Laurent, G., Nonclercq, D., Toubeau, G., Heuson-Stiennon, J.-A., Bergeron, M., & Beauchamp, D. (17 June 1992). epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats. American Journal of Physiology, 263, 806-F811.
Peer Reviewed verified by ORBi

Nonclercq, D., Wrona, S., Toubeau, G., Zanen, J., Heuson-Stiennon, J.-A., Schaudies, P., & Laurent, G. (11 April 1992). Tubular injury and regeneration in the rat kidney following acute exposure to gentamicin : a time-course study. Renal Failure, 14 (4), 507-521.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Laurent, G., Zanen, J., Schaudies, R., & Heuson-Stiennon, J.-A. (1992). Histological and ultrastructural distribution of epidermal growth factor (EGF) in rat renal tissue of rat after nephrotoxic injury. Paper presented at F.A.S.E.B. Meeting Anaheim, California, United States - California.

Léonard, I., Moulin, S., Beckers, J.-F., Laurent, G., Nonclercq, D., Zanen, J., Heuson-Stiennon, J.-A., & Falmagne, P. (1992). Decrease of epidermal growth factor (EGF) immunoreactivity in rat renal tissue during tubular regeneration. Paper presented at Société Belge de Biochimie, Rhode-St-Genèse, Belgium.

Nonclercq, D., Toubeau, G., Laurent, G., Zanen, J., Schaudies, P., & Heuson-Stiennon, J.-A. (1991). Histological and ultrastructural distribution of epidermal growth factor (EGF) in renal tissue of rat after drug-induced tubular necrosis. Paper presented at 31ème congrès de la Société Belge de Biologie Cellulaire, Mons, Belgium.

Nonclercq, D., Wrona, S., Toubeau, G., Zanen, J., Heuson-Stiennon, J.-A., Schaudies, P., & Laurent, G. (1991). Tubular injury and regeneration in the rat kidney following acute exposure to gentamicin : a time-course study. Paper presented at Seventh international symposium of nephrology, Montecatini Terme, Italy.

Toubeau, G., Nonclercq, D., Zanen, J., Lambricht, P., Tulkens, P.-M., Heuson-Stiennon, J.-A., & Laurent, G. (05 May 1991). Distribution of epidermal growth factor in the kidneys of rats exposed to amikacin. Kidney International, 40, 691-699.
Peer Reviewed verified by ORBi

Bodart, C., Nonclercq, D., Toubeau, G., Lambricht, P., Tulkens, P.-M., Heuson-Stiennon, J.-A., & Laurent, G. (1990). Immunocytochemical localization of epidermal growth factor (EGF) in rat renal tissue after treatment with Amikacin. Paper presented at 30th Annual Meeting of the American Society for cell Biology, San Diego, United States.

Laurent, G., Kishore, B. K., & Tulkens, P.-M. (01 December 1990). Aminoglycoside-induced renal phospholipidosis and nephrotoxicity. Biochemical Pharmacology, 40 (11), 2383-2392.
Peer Reviewed verified by ORBi

Tulkens, P.-M., Mingeot-Leclercq, M.-P., Laurent, G., & Brasseur, R. (1990). Conformational and biochemical analysis of the interactions between phospholipids and aminoglycoside antibiotics in relation to their toxicity. In Molecular description of Biological Membranes by Computer Aided Conformational Analysis (pp. 63-93). CRC Press.

Beauchamp, D., Laurent, G., Maldague, P., Abid, S., Kishore, B. K., & Tulkens, P.-M. (01 November 1990). Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid. Journal of Pharmacology and Experimental Therapeutics, 255 (2), 858-866.
Peer Reviewed verified by ORBi

Kishore, B. K., Kallay, Z., Lambricht, P., Laurent, G., & Tulkens, P.-M. (01 November 1990). Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro. Journal of Pharmacology and Experimental Therapeutics, 255 (2), 867-874.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Tulkens, P.-M., Heuson-Stiennon, J.-A., & Laurent, G. (18 June 1990). Renal tissue injury and proliferative response after successive treatments with anticancer platinum derivatives and tobramycin. Virchows Archiv. B: Cell Pathology, 59, 146-158.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Lambricht, P., Heuson-Stiennon, J.-A., & Laurent, G. (24 April 1990). Redistribution of epidermal growth factor immunoreactivity in renal tissue after nephrotoxin-induced tubular injury. Nephron, 57, 210-215.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Lambricht, P., Heuson-Stiennon, J.-A., & Laurent, G. (1990). Localization of EGF immunoreactivity in renal tissue during tubular regeneration. Paper presented at Société de Biologie Cellulaire de France - Colloque: 'Mécanismes de la différenciation, Oncogènes, Proto-oncogènes et facteurs de croissance', Paris, France.

Kishore, B. K., Lambricht, P., Laurent, G., Maldague, P., Wagner, R., & Tulkens, P.-M. (01 February 1990). Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids. Journal of Pharmacology and Experimental Therapeutics, 255 (2), 875-885.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Laurent, G., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (30 November 1989). Nephrotoxic injury and renal tissue repair associated with the administration of the anticancer drugs cisplatin and carboplatin. Micron and Microscopica Acta, 20 (1), 51-58.
Peer reviewed

Nonclercq, D., Toubeau, G., Laurent, G., Lambricht, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (1989). Redistribution of epidermal growth factor immunoreactivity in renal tissue after nephrotoxin-induced tubular injury. Paper presented at 29th Annual Meeting of the American Society for Cell Biology, Houtson, United States.

Nonclercq, D., Toubeau, G., Laurent, G., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (05 July 1989). Tissue injury and repair in the rat kidney after exposure to cisplatin or carboplatin. Experimental and Molecular Pathology, 51, 123-140.
Peer Reviewed verified by ORBi

Mingeot-Leclercq, M.-P., Schanck, A., Ronveaux-Dupal, M. F., Deleers, M., Brasseur, R., Ruysschaert, J.-M., Laurent, G., & Tulkens, P.-M. (01 March 1989). Ultrastructural, physico-chemical and conformational study of the interactions of gentamicin and bis(beta-diethylaminoethylether) hexestrol with negatively-charged phospholipid layers. Biochemical Pharmacology, 38 (5), 729-741.
Peer Reviewed verified by ORBi

Laurent, G., Toubeau, G., Heuson-Stiennon, J.-A., Tulkens, P.-M., & Maldague, P. (08 November 1988). Kidney tissue repair after nephrotoxic injury : biochemical and morphological characterization. Critical Reviews in Toxicology, 19 (2), 147-183.
Peer Reviewed verified by ORBi

Nonclercq, D., Toubeau, G., Laurent, G., Maldague, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (01 June 1988). Light and electron microscopic characterization of the proliferative response induced by tobramycin in rat kidney cortex. Experimental and Molecular Pathology, 48, 335-352.
Peer Reviewed verified by ORBi

Nonclercq, D., Yernaux, V., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (1988). Tissue injury and repair in the rat kidney after exposure to the anticancer agents cisplatin and carboplatin. Paper presented at Journée 'Pathologie ulltrastructurale'- Colloque Franco-Belge de Microscopie electronique, Villeneuve d'Ascq, Lille, France.

Laurent, G., Toubeau, G., Heuson-Stiennon, J. A., Tulkens, P., & Maldague, P. (09 March 1988). Kidney tissue repair after nephrotoxic injury : biochemical and morphological characterization. Critical Reviews in Toxicology, 19 (2), 147-183.
Peer Reviewed verified by ORBi

Mingeot-Leclercq, M.-P., Laurent, G., & Tulkens, P.-M. (15 February 1988). Biochemical mechanism of aminoglycoside-induced inhibition of phosphatidylcholine hydrolysis by lysosomal phospholipases. Biochemical Pharmacology, 37 (4), 591-599.
Peer Reviewed verified by ORBi

Laurent, G., Yernaux, V., Nonclercq, D., Toubeau, G., Maldague, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (11 February 1988). Tissue injury and proliferative response induced in rat kidney by cis-diamminedichloroplatinum (II). Virchows Archiv. B: Cell Pathology, 55, 129-145.
Peer Reviewed verified by ORBi

Laurent, G., Toubeau, G., Heuson-Stiennon, J. A., Tulkens, P., & Maldague, P. (09 February 1988). Kidney tissue repair after nephrotoxic injury : biochemical and morphological characterization. CRC Critical Reviews in Toxicology, 19 (2), 147-183.
Peer Reviewed verified by ORBi

Sariban, E., Kohn, K. W., Zlogotorski, C., Laurent, G., D'Incalci, M., Day, R., Smith, B. H., Kornblith, P. L., & Erickson, L. C. (01 August 1987). DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone. Cancer Research, 47 (15), 3988-3994.
Peer Reviewed verified by ORBi

Nonclercq, D., Yernaux, V., Toubeau, G., Laurent, G., & Heuson-Stiennon, J.-A. (1987). Ultrastructural characterization of tubular cells involved in repair of kidney cortex tissue after drug-induced tubular necrosis. Paper presented at Société française de Microscopie Electronique- Colloque de Biologie, Bordeaux-Talence, France.

Nonclercq, D., Toubeau, G., Laurent, G., Maldague, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (1987). Etude morphologique des cellules en prolifération dans le cortex rénal de rat traité à la tobramycine. Paper presented at Société belge de Microscopie Electronique - Colloque de Biologie, Anvers, Belgium.

Nonclercq, D., Toubeau, G., Laurent, G., Maldague, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (27 March 1987). Morphological study of proliferating cells in renal cortex of rats treated with tobramycin. Micron and Microscopica Acta, 18 (3), 203-204.
Peer reviewed

Beauchamp, D., Laurent, G., Maldague, P., & Tulkens, P.-M. (01 August 1986). Reduction of gentamicin nephrotoxicity by the concomitant administration of poly-l-aspartic acid and poly-l-asparagine in rats. Archives of Toxicology. Supplement, 9, 306-309.
Peer reviewed

Nonclercq, D., Toubeau, G., Laurent, G., Maldague, P., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (1986). Repair of kidney cortex tissue after tobramycin-induced tubular necrosis. Biochemical and ultrastructural characterization of the proliferative response. Paper presented at Société Française de Microscopie Electronique Colloque de Biologie, Nantes, France.

Toubeau, G., Maldague, P., Laurent, G., Vaamonde, C., Tulkens, P.-M., & Heuson-Stiennon, J.-A. (01 June 1986). Morphological alterations in distal and collecting tubules of the rat renal cortex after aminoglycoside administration at low doses. Virchows Archiv. B: Cell Pathology, 51 (6), 475-485.
Peer Reviewed verified by ORBi

Toubeau, G., Laurent, G., Carlier, M.-B., Abid, S., Maldague, P., Heuson-Stiennon, J.-A., & Tulkens, P.-M. (01 April 1986). Tissue repair in rat kidney cortex after short treatment with aminoglycosides at low doses. A comparative biochemical and morphometric study. Laboratory Investigation, 54 (4), 385-393.
Peer Reviewed verified by ORBi

Giurgea-Marion, L., Toubeau, G., Laurent, G., Heuson-Stiennon, J.-A., & Tulkens, P.-M. (01 February 1986). Impairment of lysosome-pinocytic vesicle fusion in rat kidney proximal tubules after treatment with gentamicin at low doses. Toxicology and Applied Pharmacology, 86 (2), 271-285.
Peer Reviewed verified by ORBi

Brasseur, R., Carlier, M.-B., Laurent, G., Claes, P. J., Vanderhaeghe, H. J., Tulkens, P.-M., & Ruysschaert, J.-M. (01 April 1985). Interaction of streptomycin and streptomycylamine derivatives with negatively charged lipid layers. Correlation between binding, conformation of complexes and inhibition of lysosomal phospholipase activities. Biochemical Pharmacology, 34 (7), 1035-1047.
Peer Reviewed verified by ORBi

Maldague, P., Laurent, G., Carlier, M.-B., & Tulkens, P.-M. (01 August 1984). A 2'guanidyl derivative of gentamicin (S86451) with reduced nephrotoxicity studies at low and medium dose levels in the rat. Archives of Toxicology. Supplement, 7, 455-458.
Peer reviewed

Giuliano, R., Paulus, G., Verpooten, G., Patijn, V., Pollet, D., Nouwen, E., Laurent, G., Carlier, M.-B., Maldague, P., Tulkens, P.-M., & De Broe, M. E. (01 June 1984). Recovery of cortical phospholipidosis and necrosis after acute gentamicin loading in rats. Kidney International, 26 (6), 838-847.
Peer Reviewed verified by ORBi

Laurent, G., Toubeau, G., Maldague, P., Carlier, M.-B., Heuson-Stiennon, J.-A., & Tulkens, P.-M. (01 April 1984). Tubular regeneration in rat kidney cortex during treatment with gentamicin at a low dose. Archives of Toxicology. Supplement, 7, 459-463.
Peer reviewed

Carlier, M.-B., Laurent, G., & Tulkens, P.-M. (01 April 1984). In vitro inhibition of lysosomal phospholipases by aminoglycoside antibiotics: a comparative study. Archives of Toxicology. Supplement, 7, 282-285.
Peer reviewed

Brasseur, R., Laurent, G., Ruysschaert, J.-M., & Tulkens, P.-M. (15 February 1984). Interactions of aminoglycoside antibiotics with negatively charged lipid layers. Biochemical and conformational studies. Biochemical Pharmacology, 33 (4), 626-637.
Peer Reviewed verified by ORBi

Porter, G. A., Laurent, G., Maldague, P., & Tulkens, P.-M. (01 February 1984). Gentamicin-induced stimulation of DNA synthesis in rat kidney. Comparison between in vivo and in vitro models. Toxicology Letters, 23 (2), 205-213.
Peer Reviewed verified by ORBi

Laurent, G., Maldague, P., Carlier, M.-B., & Tulkens, P.-M. (01 October 1983). Increased renal DNA synthesis in vivo after administration of low doses of gentamicin to rats. Antimicrobial Agents and Chemotherapy, 24 (4), 586-593.
Peer Reviewed verified by ORBi

Viau, C., Bernard, A., Lauwerys, R. R., Tulkens, P.-M., Laurent, G., & Maldague, P. (01 May 1983). Gentamicin nephrotoxicity in cadmium, lead and mercury pretreated rats. Toxicology, 27 (1), 15-25.
Peer Reviewed verified by ORBi

Carlier, M.-B., Laurent, G., Claes, P. J., Vanderhaeghe, H. J., & Tulkens, P.-M. (01 March 1983). Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies. Antimicrobial Agents and Chemotherapy, 23 (3), 440-449.
Peer Reviewed verified by ORBi

Laurent, G., Carlier, M.-B., Rollman, B., Van Hoof, F., & Tulkens, P.-M. (01 December 1982). Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin. Biochemical Pharmacology, 31 (23), 3861-3870.
Peer Reviewed verified by ORBi

Ducore, J. M., Erickson, L. C., Zwelling, L. A., Laurent, G., & Kohn, K. W. (01 March 1982). Comparative studies of DNA cross-linking and cytotoxicity in Burkitt's lymphoma cell lines treated with cis-diamminedichloroplatinum(II) and L-phenylalanine mustard. Cancer Research, 42 (3), 897-902.
Peer Reviewed verified by ORBi

Laurent, G., Erickson, L. C., Sharkey, N., & Kohn, K. W. (01 September 1981). DNA cross-linking and cytotoxicity induced by cis-diamminedichloroplatinum(II) in human normal and tumor cell lines. Cancer Research, 41 (9), 3347-3351.
Peer Reviewed verified by ORBi

Laurent, G., Laduron, C., Ruysschaert, J.-M., & Deleers, M. (01 March 1981). Inhibition of cationic liposomes of [3H]thymidine incorporation into DNA of L1210 cells. Research Communications in Chemical Pathology and Pharmacology, 31 (3), 515-529.
Peer Reviewed verified by ORBi

Erickson, L. C., Laurent, G., Sharkey, N., & Kohn, K. W. (25 December 1980). DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells. Nature, 288 (5792), 727-729.
Peer Reviewed verified by ORBi

Fruhling, J., Penasse, W., Laurent, G., Brassine, C., Hildebrand, J., Vanhaelen-Fastre, M. R., Deleers, M., & Ruysschaert, J.-M. (01 November 1980). Intracellular penetration of liposomes containing a water insoluble antimitotic drug in L1210 cells. European Journal of Cancer, 16 (05), 1409-1417.
Peer Reviewed verified by ORBi

Laurent, G., Dewerie-Vanhouche, J., Machin, D., & Hildebrand, J. (01 March 1980). Inhibition of RNA synthesis in murine ependymoblastoma by the combination of amphotericin B and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Cancer Research, 40 (3), 939-942.
Peer Reviewed verified by ORBi

Laurent, G., Doriaux, M., & Hildebrand, J. (01 April 1977). Isolation of plasma membranes from murine ependymoblastoma and subcellular distribution of amphotericin B in this tumor. Biochimica et Biophysica Acta. Biomembranes, 466 (1), 123-135.
Peer Reviewed verified by ORBi

Laurent, G., Atassi, G., & Hildebrand, J. (01 November 1976). Potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by amphotericin B in murine ependymoblastoma. Cancer Research, 36 (11), 4069-4073.
Peer Reviewed verified by ORBi

Laurent, G., Hildebrand, J., & Thys, O. (01 May 1975). Alterations of rat liver lysosomes and somooth endoplasmic reticulum induced by the diazafluoranthen derivative AC-3579. III. Mechanism and site of action. Laboratory Investigation, 32 (5), 580-584.
Peer Reviewed verified by ORBi

Contact ORBi