Profil

ANSSEAU Eugénie


Main Research Fields
Biotechnology
General & internal medicine
Zoology
Pharmacy, pharmacology & toxicology
Biochemistry, biophysics & molecular biology
Main Keywords
Atomic and Molecular Physics, and Optics; DUX4; High Energy Physics - Experiment; mesenchymal stem cells; Nuclear and High Energy Physics;
Main Unit & Research Centers
CREMH - Mind & Health
UMHAP - Centre de Recherche UMONS-Ambroise Paré
Main Co-authors
Belayew, Alexandra 
Coppée, Frédérique 
Laoudj-Chenivesse, Dalila
Tassin, Alexandra 
Vanderplanck, Céline 

Publications (total 104)

The most downloaded
4 downloads
Dmitriev, P., Bou Saada, Y., Dib, C., Ansseau, E., Barat, A., Hamade, A., Dessen, P., Robert, T., Lazar, V., Louzada, R., Dupuy, C., Zakharova, V., Carnac, G., Lipinski, M., & Vassetzky, Y. (09 August 2016). DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients. Free Radical Biology and Medicine, 99, 244-258. https://hdl.handle.net/20.500.12907/23974
The most cited
268 citations (OCI)
Dixit, M., Ansseau, E., Tassin, A., Winokur, S., Shi, R., Qian, H., Sauvage, S., Mattéotti, C., van Acker, A., Leo, O., Figlewicz, D., Barro, M., Laoudj-Chenivesse, D., Belayew, A., Coppée, F., & Chen, Y.-W. (01 November 2007). DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1. Proceedings of the National Academy of Sciences of the United States of America, 104 (46), 18157-18162. doi:10.1073/pnas.0708659104 https://hdl.handle.net/20.500.12907/9738

Derenne, A., Tassin, A., Nguyen, T. H., DeRoeck, E., Jenart, V., Ansseau, E., Belayew, A., Coppée, F., Decleves, A.-E., & Legrand, A. (2020). Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics. Scientific Reports.
Peer reviewed

Baroni, A., Neaga, I., Delbosc, N., Wells, M., Verdy, L., Ansseau, E., Vanden Eynde, J.-J., Belayew, A., Bodoki, E., Oprean, R., Hambye, S., & Blankert, B. (25 September 2019). Bioactive Aliphatic Polycarbonates Carrying Guanidinium Functions: An Innovative Approach for Myotonic Dystrophy Type 1 Therapy. ACS Omega, 4 (19), 18126 - 18135. doi:10.1021/acsomega.9b02034
Peer reviewed

Claus, C., Tomaiuolo, S., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (08 July 2019). Direct interaction of DUX4/4c with the multifunctional protein C1QBP in the FSHD pathology. Poster session presented at Advances in skeletal muscle biology in health and disease, Gainesville, United States.

Claus, C., Tomaiuolo, S., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (21 June 2019). Direct interaction of DUX4/4c with the multifunctional protein C1QBP in the FSHD pathology. Poster session presented at Discovery Worflow Toolsfo Small Molecules and Biologics-Promega, Bruxelles, Belgium.

Claus, C., Tomaiuolo, S., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (17 May 2019). Direct interaction of DUX4/4c with the multifunctional protein C1QBP in the FSHD pathology. Poster session presented at Ecole doctorale EDT-BCMB (Biologie Cellulaire et Moléculaire & Biochimie - FNRS), Bruxelles, ULB - Campus Erasme, Belgium.

Claus, C., Tomaiuolo, S., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (03 May 2019). Direct interaction of DUX4/4c with the multifunctional protein C1QBP in the FSHD pathology. Poster session presented at Mardi de la Recherche - UMONS - FWEG, Mons, Belgium.

Nguyen, T. H., Derenne, A., Ansseau, E., De Roeck, E., Coppée, F., Decleves, A.-E., Tassin, A., & Legrand, A. (27 March 2019). Development of easy outcome measures for the in vivo screening of therapeutical agents targeting DUX4 in FSHD. Poster session presented at MYOLOGY, Bordeaux, France.

Claus, C., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (20 September 2018). Direct interaction of DUX4/4c with the multifunctional protein C1QBP in the pathology FSHD. Poster session presented at Structural Dynamics In Cellular Communication, Bruxelles, Belgium.

Claus, C., Salvin, M., Tayri, T., Ansseau, E., Decleves, A.-E., Wilton, S., Kalisman, N., & Coppée, F. (08 June 2018). Direct interaction of DUX4/4c with the multifunctional protein C1QBP. Poster session presented at FSH International Research Congress, Las Vegas, United States - Nevada.

Neaga, I.-O., Hambye, S., Bodoki, E., Palmieri, C., Ansseau, E., Belayew, A., Oprean, R., & Blankert, B. (11 May 2018). Affinity capillary electrophoresis for identification of active drug candidates in myotonic dystrophy type 1. Analytical and Bioanalytical Chemistry, 410, 4495-4507.
Peer Reviewed verified by ORBi

Vanderplanck, C., Tassin, A., Ansseau, E., Charron, S., Wauters, A., Lancelot, C., Vancutsem, K., Laoudj Chevinesse, D., Belayew, A., & Coppée, F. (12 January 2018). 'Overexpression of the double homeodomain protein DUX4c interferes with myofibrillogenesis and induces clustering of myonuclei'. Skeletal Muscle, 8 (2). doi:10.1186/s13395-017-0148-4
Peer reviewed

Ansseau, E., Sciot, M., Goudji, C., Castella, S., Larcher, J.-C., Belayew, A., & Coppée, F. (2017). FSHD and OPMD: Deregulation of IGF2BP1-mRNP components during the differentiation of FSHD muscle cells. Paper presented at 22nd International Congress of the Word Muscle Society, Saint Malo, France.

Ansseau, E. (2017). Deregulation of IGF2BP1-mRNP components during the differentiation of FSHD muscle cells. Paper presented at World Muscle Society, Saint-Malo, France.

Neaga, I.-O., Hambye, S., Bodoki, E., Ansseau, E., Blankert, B., & Oprean, R. (22 May 2017). Affinity capillary electrophoresis as fast screening method for the identification of potentially active compounds for DM1 treatment. Poster session presented at The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Prague, Czechia.

Ansseau, E., Vanderplanck, C., Wauters, A., Harper, S. Q., Coppée, F., & Belayew, A. (03 March 2017). Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD). Genes, 8 (3), 93. doi:10.3390/genes8030093
Peer Reviewed verified by ORBi

Ansseau, E. (11 December 2016). Les maladies héréditaires du muscle du gène au médicament. Paper presented at Réunion ordinaire de la Société des Sciences, des arts et des Lettres du Hainaut, Mons, Belgium.

Ansseau, E., Lancelot, C., Wauters, A., Vanderplanck, C., Belayew, A., & Coppée, F. (10 November 2016). Transcription factors DUX4 and DUX4c associate with mRNP granules in the cytoplasm of fusing myoblasts: a new function in translation regulation? Poster session presented at FSH Society, Boston, United States - Massachusetts.

Ansseau, E., Lancelot, C., Belayew, A., & Coppée, F. (04 October 2016). Transcription factors DUX4 and DUX4c associate with mRNP granules in the cytoplasm of fusing myoblasts: a new function in translation regulation? Poster session presented at 21st International WMS Congress, Granada, Spain.

Dmitriev, P., Bou Saada, Y., Dib, C., Ansseau, E., Barat, A., Hamade, A., Dessen, P., Robert, T., Lazar, V., Louzada, R., Dupuy, C., Zakharova, V., Carnac, G., Lipinski, M., & Vassetzky, Y. (09 August 2016). DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients. Free Radical Biology and Medicine, 99, 244-258.
Peer Reviewed verified by ORBi

Ansseau, E. (04 May 2016). 'Homologous DUX transcription factors, involved in Facioscapulohumeral muscular dystrophy, interact with cytoplasmic proteins during muscle differentiation '. Paper presented at Séminaire Life Science - UNamur, Namur, Belgium.

Ansseau, E. (21 April 2016). 'Homologous DUX transcription factors, involved in Facioscapulohumeral muscular dystrophy, interact with cytoplasmic proteins during muscle differentiation '. Paper presented at Séminaire d'unité - INSERM U1046, Montpellier, France.

Ansseau, E. (31 March 2016). 'Homologous DUX transcription factors, involved in Facioscapulohumeral muscular dystrophy, interact with cytoplasmic proteins during muscle differentiation '. Paper presented at Séminaire UCL, Woluwé, Belgium.

Ansseau, E., O, J., Lancelot, C., Tassin, A., Matteoti, C., Yip, C., Liu, J., Leroy, B., Hubeau, C., Gerbaux, C., Cloet, S., Wauters, A., Zorbo, S., Meyer, P., Pirson, I., Laoudj Chevinesse, D., Wattiez, R., Harper, S., Belayew, A., & Coppée, F. (14 March 2016). The translocation of DUX4 and DUX4c during myoblast differentiation allows their association with nucleo-cytoplasmic proteins associated with mRNP granules. Poster session presented at International Congress Of Myology, Lyon, France.

De La Kethulle De Ryove, L., Ansseau, E., Nachtegael, C., Pieters, K., Vanderplanck, C., Geens, M., Sermon, K., Wilton, S., Coppée, F., Lagneaux, L., & Belayew, A. (14 March 2016). The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow. Poster session presented at 5th International Congress of Myology, Lyon, France.

Vanderplanck, C., Tassin, A., Ansseau, E., Lancelot, C., Derenne, A., Conotte, S., Dudome, V., Leroy, B., Wilton D., S., Laoudj-Chenivesse, D., Wattiez, R., Legrand, A., Belayew, A., & Coppée, F. (14 March 2016). 'Antisense strategies targeting DUX4 and DUX4c for the treatment of Facioscapulohumeral muscular dystrophy.'. Poster session presented at 5th International Congress of Myology, Lyon, France.

Ansseau, E., Eidal, J., Lancelot, C., Tassin, A., Matteotti, C., Yip, C., Liu, J., Leroy, B., Hubeau, C., Gerbaux, C., Cloet, S., Wauters, A., Zorbo, S., Meyer, P., Pirson, I., Laoudj-Chenivesse, D., Wattiez, R., Harper, S. Q., Belayew, A., & Coppée, F. (2016). Homologous transcription factors DUX4 and DUX4c associate with cytoplasmic proteins during muscle differentiation. PLoS ONE.
Peer reviewed

Ansseau, E., & Coppée, F. (18 January 2016). « Homologous DUX transcription factors interact with cytoplasmic proteins during muscle differentiation. Paper presented at Séminaires de l'institut de Myologie, Paris, France.

Ansseau, E., Eidahl, J. O., Lancelot, C., Tassin, A., Matteoti, C., Yip, C., Liu, J., Leroy, B., Hubeau, C., Gerbaux, C., Cloet, S., Wauters, A., Zorbo, S., Meyer, P., Pirson, I., Laoudj-Chenivesse, D., Wattiez, R., Harper, S. Q., Belayew, A., & Coppée, F. (06 October 2015). The translocation of DUX4 and DUX4c during myoblast differentiation allows their association with nucleo-cytoplasmic proteins associated with mRNP granules. Paper presented at FSH society, Boston, United States - Massachusetts.

De La Kethulle De Ryhove, L., Ansseau, E., Nachtegael, C., Pieters, K., Vanderplanck, C., Geens, M., Sermon, K., Wilton D., S., Coppée, F., Lagneaux, L., & Belayew, A. (06 October 2015). The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow. Paper presented at FSH Society, Boston, United States - Massachusetts.

Ansseau, E., Eidahl, J. O., Lancelot, C., Tassin, A., Matteoti, C., Yip, C., Liu, J., Leroy, B., Hubeau, C., Gerbaux, C., Cloet, S., Wauters, A., Zorbo, S., Meyer, P., Pirson, I., Laoudj-Chenivesse, D., Wattiez, R., Harper, S. Q., Belayew, A., & Coppée, F. (04 October 2015). Unexpected location of DUX4/4c transcription factors in the cytoplasm suggests a role in mRNP granules and translation regulation. Poster session presented at International World Muscle Society Congress, Brighton, United Kingdom.

Vanderplanck, C., Tassin, A., Ansseau, E., Lancelot, C., Derenne, A., Conotte, S., Dudome, V., Leroy, B., Wilton D., S., Laoudj-Chenivesse, D., Wattiez, R., Legrand, A., Belayew, A., & Coppée, F. (2015). Antisense strategies targeting DUX4 and DUX4c for the treatment of Facioscapulohumeral muscular dystrophy. Paper presented at International World Muscle Society congress, Brighton, United Kingdom.

De La Kethulle De Ryhove, L., Ansseau, E., Nachtegael, C., Pieters, K., Vanderplanck, C., Geens, M., Sermon, K., Wilton D., S., Coppée, F., Lagneaux, L., & Belayew, A. (20 July 2015). The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow. Stem Cells and Development, 24 (22), 2674-86. doi:10.1089/scd.2014.0575
Peer Reviewed verified by ORBi

Vanderplanck, C., Tassin, A., Ansseau, E., Lancelot, C., Derenne, A., Conotte, S., Dudome, V., Leroy, B., Wilton D., S., Laoudj-Chenivesse, D., Wattiez, R., Legrand, A., Belayew, A., & Coppée, F. (22 May 2015). Antisense strategies targeting DUX4 and DUX4c for the treatment of Facioscapulohumeral muscular dystrophy. Poster session presented at Journée UMHAP from lab to bedside, Mons, Belgium.

Vanderplanck, C., Tassin, A., Ansseau, E., Lancelot, C., Derenne, A., Conotte, S., Dudome, V., Leroy, B., Wilton D., S., Laoudj-Chenivesse, D., Wattiez, R., Legrand, A., Belayew, A., & Coppée, F. (17 April 2015). Antisense strategies targeting DUX4 and DUX4c for the treatment of facioscapulohumeral muscular dystrophy (FSHD. Poster session presented at Novel Therapies for monogennic diseases, Paris, France.

Vanderplanck, C., Tassin, A., Ansseau, E., Lancelot, C., Derenne, A., Conotte, S., Dudome, V., Leroy, B., Wilton D., S., Laoudj-Chenivesse, D., Wattiez, R., Legrand, A., Belayew, A., & Coppée, F. (15 April 2015). Antisense strategies targeting DUX4 and DUX4c for the treatment of Facioscapulohumeral muscular dystrophy. Poster session presented at symposium de thérapie génique du Collège de France, Paris, France.

Ansseau, E., Domire, J. S., Wallace, L. M., Eidahl, J. O., Guckes, S. M., Giesige, C. R., Pyne, N. K., Belayew, A., & Harper, S. Q. (2015). Aberrant Splicing in Transgenes Containing Introns, Exons, and V5 Epitopes: Lessons from Developing an FSHD Mouse Model Expressing a D4Z4 Repeat with Flanking Genomic Sequences. PLoS ONE.
Peer reviewed

De La Kethulle De Ryhove, L., Ansseau, E., Nachtegael, C., Pieters, K., Vanderplanck, C., Geens, M., Sermon, K., Wilton D., S., Coppée, F., Lagneaux, L., & Belayew, A. (11 February 2015). The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow. Poster session presented at Télévie's Research Seminar, ULB-Erasme, Belgium.

Ansseau, E. (01 December 2014). Antisense strategies against DUX4 as a therapeutic approach for FSHD. Proceedings of the Belgian Royal Academies of Medicine, 3, 194-204.
Peer Reviewed verified by ORBi

Ansseau, E., Matteoti, C., Tassin, A., Lancelot, C., Leroy, B., Hubeau, C., Nachtegael, C., Gerbaux, C., Zorbo, S., Cloet, S., Yip, C., Meyer, P., Carnac, G., Laoudj-Chenivesse, D., Wattiez, R., Belayew, A., & Coppée, F. (17 October 2014). Unexpected role for DUX transcription factors into the cytoplasm. Paper presented at International Research Consortium & Research Planning Meetings, San Diego, United States - California.

Lancelot, C., Ansseau, E., Tassin, A., Matteoti, C., Leroy, B., Gerbaux, C., Zorbo, S., Cloet, S., Yip, C., Laoudj-Chenivesse, D., Wattiez, R., Belayew, A., & Coppée, F. (06 July 2014). Study of the double homeodomain DUX protein partners: focus on the interaction with desmin. Paper presented at IF-NMD Workshop Nice 2014 - Satellite Workshop to ICNMD, Nice, France.

Tassin, A., Ansseau, E., Matteotti, C., Lancelot, C., Leroy, B., Gerbaux, C., Zorbo, S., Cloet, S., Yip, C., Laoudj-Chenivesse, D., Wattiez, R., Belayew, A., & Coppée, F. (14 May 2014). Study of the double homeodomain DUX protein partners highlights DUX4c involvement in human muscle regeneration. Paper presented at EMBO Conference : Molecular Biology of Muscle Development and Regeneration, Acaya-Lecce, Italy.

De La Kethulle De Ryhove, L., Ansseau, E., Geens, M., Coppée, F., Sermon, K., Lagneaux, L., & Belayew, A. (2014). DUX4 expression during Osteogenic Differentiation in MSCs. Paper presented at 20th ISCT Annual Meeting (International Society Cellular Therapy) 2014, Palais des Congrès, Paris, France.

De La Kethulle De Ryhove, L., Ansseau, E., Geens, M., Coppée, F., Sermon, K., Lagneaux, L., & Belayew, A. (25 April 2014). DUX4 expression during Osteogenic Differentiation in MSCs. Poster session presented at 20th ISCT Annual Meeting (International Society Cellular Therapy) 2014, Palais des Congrès, Paris, France.

De La Kethulle De Ryhove, L., Ansseau, E., & Belayew, A. (2014). Mise à jour de la séquence AF117.653 (Homo sapiens double homeobox protein genes, complete cds).

Dmitriev, P., Stankevicins, L., Ansseau, E., Petrov, A., Barat, A., Dessen, P., Robert, T., Turki, A., Lazar, V., Labourer, E., Belayew, A., Carnac, G., Laoudj-Chenivesse, D., Lipinski, M., & Vassetzky, Y. (06 December 2013). Defective Regulation of MicroRNA Target Genes in Myoblasts from Facioscapulohumeral Dystrophy Patients. Journal of Biological Chemistry, 288, 34989-35002.
Peer Reviewed verified by ORBi

De La Kethulle De Ryhove, L., Ansseau, E., Geens, M., Coppée, F., Sermon, K., Lagneaux, L., & Belayew, A. (05 December 2013). DUX4 expression during Osteogenic Differentiation in MSCs. Poster session presented at Journée des jeunes chercheurs Télévie, Université Catholique de Louvain, Belgium.

Vanderplanck, C., Tassin, A., Lancelot, C., Ansseau, E., Nonclercq, D., Delrée, P., Laoudj-Chenivesse, D., Belayew, A., & Coppée, F. (27 November 2013). DUX4c, a DUX4-homologue, causes the FSHD disorganized myotube phenotype: an additional target for therapeutic strategies. Paper presented at Colloque Myogenèse XVI, Montpellier, France.

Ansseau, E., Charron, S., Laoudj-Chenivesse, D., Coppée, F., & Belayew, A. (21 October 2013). Interplay between Sp1, YY1 and MYOD in transcription regulation of the DUX4 gene that causes facioscapulohumeral muscular dystrophy (FSHD). Paper presented at FSH Society (FacioScapuloHumeral Muscular Dystrophy) International Reasearch Consortium & Reasearch Planning Meeting, Boston, United States - Massachusetts.

Ansseau, E. (07 September 2013). Antisense strategies against DUX4 as a therapeutic approach for FSHD. Paper presented at Remise des prix de Académie Royale de Médecine de Belgique, Bruxelles, Belgium.

Hambye, S., Ansseau, E., Carminati, A., Vanden Eynde, J.-J., Belayew, A., & Blankert, B. (30 June 2013). Strategies for the development of a screening test in myotonic dystrophy type 1. Application to a new library of synthetized pentamidine analogs. Poster session presented at 24th International Symposium on Pharmaceutical and Biomedical Analysis, Bologne, Italy.

De La Kethulle De Ryhove, L., Ansseau, E., Coppée, F., & Belayew, A. (06 June 2013). DUX4 expression in embryonic stem cells. Poster session presented at 3rd Heidelberg forum for young life scientists, DFKZ, Heidelberg, Germany.

Hambye, S., Neaga, I.-O., Carminati, A., Ansseau, E., Vanden Eynde, J.-J., Bodoki, E., Sandulescu, R., Belayew, A., & Blankert, B. (01 June 2013). Study of nucleic acids-ligands interactions by two different strategies. Application to Myotonic Dystrophy type 1. Poster session presented at Health Institute Day, Mons, Umons, Belgium.

Tassin, A., Vanderplanck, C., Ansseau, E., Derenne, A., Coppée, F., & Belayew, A. (24 May 2013). Different approaches to evaluate antisense strategies against the causal gene of the FSHD myopathy. Poster session presented at Journée de l'Institut de recherche en sciences et technologies de la santé, Mons, Belgium.

De La Kethulle De Ryhove, L., Geens, M., dimitrova, J., Ansseau, E., Sermon, K., & Belayew, A. (24 May 2013). DUX4 expression in embryonic stem cells. Poster session presented at Journée de l'institut santé, Mons, Belgium.

Ansseau, E., Vanderplanck, C., Wallace, L. M., Tassin, A., Domire, J. S., Guckes, S. M., Yip, C., Laoudj-Chenivesse, D., Coppée, F., Wilton D., S., Harper, S. Q., & Belayew, A. (24 May 2013). Evaluation of new antisense oligomers targeting the DUX4 mRNA. Poster session presented at Journée de l'Institut de recherche en sciences et technologies de la santé, Mons, Belgium.

Ansseau, E., Vanderplanck, C., Wallace, L. M., Tassin, A., Domire, J. S., Guckes, S. M., Yip, C., Laoudj-Chenivesse, D., Coppée, F., Wilton D., S., Harper, S. Q., & Belayew, A. (22 April 2013). Evaluation of new antisense oligomers targeting the DUX4 mRNA as a therapeutic strategy for FSHD. Paper presented at MDA Scientific Conference, Washington DC, United States - District of Columbia.

De La Kethulle De Ryhove, L., Ansseau, E., Coppée, F., & Belayew, A. (12 March 2013). Study of DUX4 expression and function in non-muscular cells. Poster session presented at 7ème édition de la Matinée de Chercheurs, Mons, Belgium.

Hambye, S., Ansseau, E., Helvenstein, M., Carminati, A., Vanden Eynde, J.-J., Belayew, A., & Blankert, B. (12 March 2013). Analytical developments and biological evaluation (in Steinert desease) of Pentamidine and new analogs. Poster session presented at 7ième Matinée des Chercheurs, Mons, Belgium.

Dhont, L., Denis, O., Ansseau, E., & Belayew, A. (29 January 2013). Study of the Helicase-like Transcription Factor protein partners. Poster session presented at Journée Scientifique des Doctorants en Sciences biomédicales et pharmaceutiques; New tools and strategies in the identification of pathology-related biomarkers, Mons, Belgium.

Hambye, S., Ansseau, E., Vanden Eynde, J.-J., Belayew, A., & Blankert, B. (29 January 2013). Strategies for the development of a new screening test in myotonic dystrophy (type I). Application to a new library of synthetized pentamidine analogs. Poster session presented at Journée Scientifique des Doctorants en Sciences Biomédicales et Pharmaceutiques - NEW TOOLS AND STRATEGIES IN THE IDENTIFICATION OF PATHOLOGY-RELATED BIOMARKERS, Mons, Belgium.

Tassin, A., Laoudj-Chenivesse, D., Vanderplanck, C., Barro, M., Charron, S., Ansseau, E., Chen, Y.-W., Mercier, J., Coppée, F., & Belayew, A. (01 January 2013). DUX4 expression in FSHD muscle cells: how could such a rare protein cause a myopathy? Journal of Cellular Molecular Medecine, 17 (1), 1-15. doi:10.1111/j.1582-4934.2012.01647.x
Peer reviewed

De La Kethulle De Ryhove, L., Dimitrova, J., Ansseau, E., Geens, M., Lagneaux, L., Sermon, K., Coppée, F., & Belayew, A. (10 December 2012). DUX4 expression in non-muscle cells. Poster session presented at Télévie 2013, Liège, Belgium.

Dhont, L., Olivia, D., Ansseau, E., & Belayew, A. (10 December 2012). Study of the Helicase-like Transcription Factor protein partners. Poster session presented at Télévie 2013, Liège, Belgium.

Tassin, A., Vanderplanck, C., Leroy, B., Charron, S., Ansseau, E., Wauters, A., Laoudj-Chenivesse, D., Wattiez, R., Belayew, A., & Coppée, F. (07 November 2012). Investigations on the FSHD disorganized myotube phenotype. Poster session presented at FSH Society International Reasearch Consortium Meeting, San Francisco, United States.

Ansseau, E., Vanderplanck, C., Wallace, L. M., Tassin, A., Domire, J. S., Guckes, S. M., Yip, C., Laoudj-Chenivesse, D., Coppée, F., Wilton D., S., Harper, S. Q., & Belayew, A. (06 November 2012). Evaluation of new antisense oligomers targeting the DUX4 mRNA as a therapeutic strategy for FSHD. Paper presented at FSH Society International Reasearch Consortium Meeting, San Francisco, United States.

Hambye, S., Ansseau, E., Vanden Eynde, J.-J., Belayew, A., & Blankert, B. (16 October 2012). Strategies for the development of a new screening test in myotonic dystrophy (type I). Application to a new library of synthetized pentamidine analogs. Poster session presented at Journées des doctorants de l'Unité Doctorale en Sciences Pharmaceutiques ULB/UMons, Bruxelles, Belgium.

Ansseau, E., Mattéotti, C., Gerbaux, C., Yip, C., Pire, E., Vachaudez, V., Cloet, S., Wattiez, R., Coppée, F., & Belayew, A. (07 November 2011). DUX4 and DUX4c protein partners in muscle cells. Poster session presented at FSH Society (FSHD) 2011 International Research Consortium and Researchplanning meetings, Boston, United States - Massachusetts.

Tassin, A., Laoudj-Chenivesse, D., Charron, S., Ansseau, E., Chen, Y.-W., Mercier, J., Coppée, F., & Belayew, A. (07 November 2011). Detection of endogenous DUX4 protein in FSHD muscles: could the spreading of a rare protein cause FSHD? Poster session presented at FSH Society International Research Consortium & Reasearch Planning Meeting, Boston, United States - Massachusetts.

Vanderplanck, C., Ansseau, E., Charron, S., Stricwant, N., Tassin, A., Laoudj-Chenivesse, D., Wilton D., S., Coppée, F., & Belayew, A. (01 November 2011). The FSHD atrophic myotube phenotype is caused by DUX4 expression and corrected by its suppression. PLoS ONE, 6 (10), 26820. doi:10.1371/journal.pone.0026820
Peer reviewed

Dmitriev, P., Petrov, A., Ansseau, E., Stankevicins, L., Charron, S., Kim, E., Bos, T., Robert, T., Turki, A., Coppée, F., Belayew, A., Lazar, V., Carnac, G., Laoudj-Chenivesse, D., Lipinski, M., & Vassetzky, Y. (21 September 2011). The Kruppel-like Factor 15 as a Molecular Link between Myogenic Factors and a Chromosome 4q Transcriptional Enhancer Implicated in Facioscapulohumeral Dystrophy. Journal of Biological Chemistry, 286, 44620-44631.
Peer Reviewed verified by ORBi

Tassin, A., Leroy, B., Ansseau, E., Pire, E., Faille, J., Leclercq, T., Charron, S., Vanderplanck, C., Wauters, A., Turky, D., Laoudj-Chenivesse, D., Coppée, F., Wattiez, R., & Belayew, A. (12 May 2011). The galectin-1 gene is activated in FSHD Myotubes as a result of the DUX4 transcriptional deregulation cascade. Poster session presented at 4th international congress of myology 2011, Lille , France.

Vanderplanck, C., Coppée, F., Ansseau, E., Tassin, A., Charron, S., Laoudj-Chenivesse, D., Wilton D., S., & Belayew, A. (12 May 2011). Interfering with the transcription deregulation cascades in fshd. Paper presented at 4th international congress of myology 2011, Lille , France.

Ansseau, E., Charron, S., Guiguen, A., Van Lint, C., Coppée, F., & Belayew, A. (12 May 2011). YY1 and MyoD are transcriptional activator and inhibitor, respectively, of the DUX4 gene that causes facioscapulohumeral muscular dystrophy (FSHD). Poster session presented at 4th international congress of myology 2011, Lille , France.

Vanderplanck, C., Ansseau, E., Charron, S., Tassin, A., Turki, A., Laoudj-Chenivesse, D., Wilton D., S., Coppée, F., & Belayew, A. (06 May 2011). SUPPRESSION OF DUX4 OR DUX4C EXPRESSION BY ANTISENSE STRATEGIES IN A THERAPEUTIC APPROACH FOR FSHD. Paper presented at 7th AGTS Meeting, Melbourne, Australia.

Ansseau, E., Charron, S., Guiguen, A., Van Lint, C., Coppée, F., & Belayew, A. (22 March 2011). YY1 and MyoD are transcriptional activator and inhibitor, respectively, of the DUX4 gene that causes facioscapulohumeral muscular dystrophy (FSHD). Poster session presented at La matinée des chercheurs, Mons, Unknown/unspecified.

Vanderplanck, C., Coppée, F., Ansseau, E., Tassin, A., Charron, S., Laoudj-Chenivesse, D., Wilton D., S., & Belayew, A. (14 March 2011). Suppression of DUX4 or DUX4c protein expression by antisense strategies in a therapeutic approach for FSHD. Paper presented at MDA national scientific conference Neuromuscular Therapeutic Strategies: Overcoming the Barriers from Microscope to Marketplace, Las Vegas, United States - Nevada.

Tassin, A., Leroy, B., Ansseau, E., Pire, E., Faille, J., Leclercq, T., Charron, S., Laoudj-Chenivesse, D., Coppée, F., Wattiez, R., & Belayew, A. (25 November 2010). Focus on nuclear proteins of FSHD primary myotubes by differential mass spectrometry. Poster session presented at VIIIè journées annuelles Société Française de Myologie, Nice, France.

Tassin, A., Leroy, B., Ansseau, E., Pire, E., Charron, S., Coppée, F., Wattiez, R., & Belayew, A. (25 October 2010). Focus on nuclear proteins of FSHD primary myotubes by differential mass spectrometry. Poster session presented at FSHD International Research Consortium Meeting, Boston, United States - Massachusetts.

Vanderplanck, C., Coppée, F., Ansseau, E., Tassin, A., Laoudj-Chenivesse, D., Wilton D., S., & Belayew, A. (21 October 2010). Suppression of DUX4 or DUX4c protein expression by antisense strategies as a therapeutic approach for FSHD. Paper presented at FSH Society International Research Consortium & Research Planning Meeting, Boston, United States - Massachusetts.

Vanderplanck, C., Ansseau, E., Coppée, F., Belayew, A., & Wilton D., S. (01 September 2010). Agents useful in treating Facioscapulohumeral muscular dystrophy.

Dmitriev, P., Petrov, A., Ansseau, E., Charron, S., Coppée, F., Belayew, A., Carnac, G., Turki, A., Laoudj-Chenivesse, D., Lipinski, M., & Vassetzky, Y. (06 November 2009). Kruppel-like factor KLF15 interacts with the D4Z4 enhancer and upregulates a FSHD-related gene DUX4c. Poster session presented at FSH Society International Research Consortium and Research Planning Meetings, Boston, United States - Massachusetts.

Ansseau, E., Laoudj-Chenivesse, D., Marcowycz, A., Tassin, A., Vanderplanck, C., Sauvage, S., Barro, M., Mahieu, I., Leroy, A., Leclercq, I., Mainfroid, V., Figlewicz, D., Mouly, V., Butler-Browne, G., Belayew, A., & Coppée, F. (01 October 2009). DUX4c Is Up-Regulated in FSHD. It Induces the MYF5 Protein and Human Myoblast Proliferation. PLoS ONE, 4 (10), 7482. doi:10.1371/journal.pone.0007482
Peer reviewed

Tassin, A., Vanderplanck, C., Ansseau, E., Marcowyzc, A., Barro, M., Laoudj-Chenivesse, D., Belayew, A., & Coppée, F. (26 May 2008). Studies on the expression and function of DUX4c, a gene located close to the FSHD locus. Poster session presented at 3ème Congrès International de Myologie, Marseille, France.

Tassin, A., Ansseau, E., Vanderplanck, C., Cloet, S., Barro, M., Laoudj-Chenivesse, D., Chen, Y.-W., Belayew, A., & Coppée, F. (21 January 2008). DUX4 and DUX4c activate different pathways in Facioscapulohumeral dystrophy. Paper presented at Colloque « Myogenese IX », Institut de Myologie, Paris, France.

Tassin, A., Vanderplanck, C., Ansseau, E., Cloet, S., Barro, M., Laoudj-Chenivesse, D., Dabauvalle, M. C., Wehnert, M., Chen, Y.-W., Belayew, A., & Coppée, F. (2008). Study of DUX4 and DUX4c in facioscapulohumeral muscular dystrophy. Paper presented at 13th International WMS Congress, Newcastle upon Tyne, United Kingdom.

Ansseau, E., Tassin, A., Vanderplanck, C., Cloet, S., Barro, M., Laoudj-Chenivesse, D., Chen, Y.-W., Belayew, A., & Coppée, F. (04 November 2007). Further studies on the DUX4, DUX4c and PITX1 genes in FSHD. Paper presented at FSHD international Workshop meeting, San Diego, United States - California.

Dixit, M., Ansseau, E., Tassin, A., Winokur, S., Shi, R., Qian, H., Sauvage, S., Mattéotti, C., van Acker, A., Leo, O., Figlewicz, D., Barro, M., Laoudj-Chenivesse, D., Belayew, A., Coppée, F., & Chen, Y.-W. (01 November 2007). DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1. Proceedings of the National Academy of Sciences of the United States of America, 104 (46), 18157-18162. doi:10.1073/pnas.0708659104
Peer Reviewed verified by ORBi

Kowaljow, V., Marcowycz, A., Ansseau, E., Conde, C. B., Sauvage, S., Mattéotti, C., Arias, C., Corona, E. D., Nuñez, N. G., Leo, O., Wattiez, R., Figlewicz, D., Laoudj-Chenivesse, D., Belayew, A., Coppée, F., & Rosa, A. L. (01 June 2007). The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein. Neuromuscular Disorders, 17 (8), 611-23. doi:10.1016/j.nmd.2007.04.002
Peer Reviewed verified by ORBi

Tassin, A., Ansseau, E., Sauvage, S., Mattéotti, C., Van Acker, A.-M., Figlewicz, D., Laoudj-Chenivesse, D., Oberdan, L., Coppée, F., & Belayew, A. (18 December 2006). Evidence for the expression of the DUX4 gene in primary myoblasts of patients affected with Facioscapulohumeral muscular dystrophy. Poster session presented at 194th Congrès de la Société Belge de Biochimie et de Biologie Moléculaire / 'Young Scientists Day, Gembloux, Belgium.

Ansseau, E., Laoudj-Chenivesse, D., Marcowycz, A., Sauvage, S., Barro, M., Tassin, A., Mattéotti, C., van Acker, A., Leroy, A., Leclercq, I., Leo, O., Figlewicz, D., Belayew, A., & Coppée, F. (2006). Characterization of the DUX4c gene located within a repeated element close to the FSHD locus. Paper presented at 11th International Congress of the World Muscle Society, Bruges, Belgium.

Ansseau, E., Tassin, A., Sauvage, S., Laoudj-Chenivesse, D., Barro, M., Figlewicz, D., Coppée, F., & Belayew, A. (09 October 2006). DUX4 gene expression in FSHD primary myoblasts. Paper presented at FSHD International Consortium Research Meeting, New Orleans, United States - Louisiana.

Ansseau, E., Coppée, F., & Belayew, A. (20 May 2006). Fonctional characterization of the DUX4 et DUX4c genes located within repeated elements at the FSHD locus. Poster session presented at Bioforum, Liège, Belgium.

Ansseau, E., Laoudj-Chenivesse, D., Marcowycz, A., Barro, M., Sauvage, S., Mattéotti, C., Mahieu, I., Tassin, A., Van Acker, A.-M., Leo, O., Fliglewicz, D., Coppée, F., & Belayew, A. (13 January 2006). Etude de DUX4 et DUX4c, gènes candidats pour la FSHD. Paper presented at Club muscle 'V', Paris, France.

Laoudj-Chenivesse, D., Barro, M., Sauvage, S., Tassin, A., Ansseau, E., Marcowycz, A., Figlewicz, D., Van Acker, A.-M., Leo, O., Belayew, A., & Coppée, F. (25 October 2005). Overexpression of the double homeodomain protein DUX4c in FSHD muscle. Paper presented at FSHD International Consortium Research Meeting, Salt Lake City, United States - Utah.

Belayew, A., Ansseau, E., Sauvage, S., Marcowycz, A., Laoudj-Chenivesse, D., Carnac, G., Mattéotti, C., Gerbaux, C., Mahieu, I., Zorbo, S., Leclercq, I., Tassin, A., Figlewicz, D., & Coppée, F. (09 June 2005). Etude fonctionnelle de DUX4 et DUX4c, et de leur rôle dans la dystrophie de Landouzy-Dejerine. Paper presented at Meeting « Club Muscle IV », Marseille, France.

Ansseau, E., Sauvage, S., Laoudj-Chenivesse, D., Carnac, G., Marcowyzc, A., Leroy, A., Leclercq, I., Figlewicz, D., Belayew, A., & Coppée, F. (27 May 2005). Characterization of DUX4c, a double homeobox gene located in a truncated and inverted D4Z4 element, and its expression in FSHD mlyoblasts. Poster session presented at 190th meeting of the Belgian Society of Biochemistry and Molecular Biology, Mons, Belgium.

Ansseau, E., Sauvage, S., Laoudj-Chenivesse, D., Carnac, G., Marcowycz, A., Leroy, A., Leclercq, I., Figlewicz, D., Belayew, A., & Coppée, F. (09 May 2005). Characterization of DUX4c, a double homeobox gene located in a truncated and inverted D4Z4 element, and its expression in FSHD mlyoblasts. Poster session presented at Congrès Myologie 2005, Nantes, France.

Ansseau, E., Coppée, F., D'Amico, E., Marcowycz, A., Mattéotti, C., Sauvage, S., Wiilocq, J., & Belayew, A. (26 October 2004). Functional study of the DUX4 and DUX4c genes. Paper presented at FSHD International Consortium Research Meeting, Toronto, Canada.

Coppée, F., Mattéotti, C., Ansseau, E., Sauvage, S., Leclercq, I., Leroy, A., Marcowyzc, A., Gerbaux, C., Figlewicz, D., Ding, H., & Belayew, A. (2004). The DUX gene family and FSHD. In Facioscapulohumeral Muscular Dystrophy: Clinical Medicine and Molecular Biology (pp. 117-134). Bios. Scientific publisher.

Ansseau, E., Coppée, F., & Belayew, A. (2003). Publication of a sequence in GeneBank 'accession num. EMBL/Genbank: AY500824 :Homo sapiens double homeobox4c (DUX4c) gene, complete cds'.

Marcowyzc, A., Ansseau, E., Sauvage, S., Mattéotti, C., Zorbo, S., Belayew, A., & Coppée, F. (04 November 2003). Characterization of DUX4c and its role in facioscapulohumeral dystrophy (FSHD). Poster session presented at FSHD International Consortium Research Meeting, Los Angeles, United States.

Ansseau, E., Coppée, F., & Belayew, A. (01 October 2003). Etude de l'élément cis répresseur du locus D4Z4 et de son rôle dans l'expression de DUX4, un gène candidat pour la dystrophie facio-scapulo-humérale (FSHD). Poster session presented at 1ère journées annuelles de Société Française de Myologie, Caen, France.

Marcowycz, A., Ansseau, E., Coppée, F., & Belayew, A. (01 October 2003). Caractérisation du gène et de la protéine DUX4c. Paper presented at 1ère journées annuelles de la société française de Myologie, Caen, France.

Ansseau, E., Sauvage, S., Mattéotti, C., Marcowyzc, A., Belayew, A., & Coppée, F. (30 September 2003). Functional study of the DUX4 gene. Poster session presented at FSHD International Consortium Research Meeting, Los Angeles, United States.

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