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Conotte Raphael

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Service du Doyen de la Faculté de Médecine et Pharmacie

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Service de Biologie humaine et Toxicologie

Université de Mons - UMONS > Faculté des Sciences > Service d'Ecologie numérique

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Service de Biochimie métabolique et moléculaire

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Biologie humaine et Toxicologie

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > FMP - Service du Doyen

Main Referenced Co-authors
COLET, Jean-Marie  (41)
TAGLIATTI, Vanessa  (14)
De luca, Deborah  (9)
BLANKERT, Bertrand  (6)
Helvenstein, Maxime  (5)
Main Referenced Keywords
Biological Data Science (2); Data Science Teaching (2); Teaching (2); Biochemistry (1); Cancer (1);
Main Referenced Unit & Research Centers
UMHAP - Centre de Recherche UMONS-Ambroise Paré (14)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (19)
Architecture (10)
Oncology (8)
Radiology, nuclear medicine & imaging (8)
Immunology & infectious disease (5)

Publications (total 53)

The most downloaded
12 downloads
Grosjean, P., Engels, G., & Conotte, R. (2020). BioDataScience1: A Series of Learnr Documents for Biological Data Science course 1: An R package for teaching biological data science. https://hdl.handle.net/20.500.12907/25666

The most cited

53 citations (Scopus®)

Valentini, X., Rugira Uwamahoro, P., Frau, A., Tagliatti, V., Conotte, R., Laurent, S., Colet, J.-M., & Nonclercq, D. (03 March 2019). Hepatic and renal toxicity induced by TiO2 nanoparticles in rats : a morphological and metabonomic study. Journal of Toxicology, 2019. https://hdl.handle.net/20.500.12907/19213

Maroil, D., Labiau, L., Conotte, R., & Colet, J.-M. (In press). Exploration de l'effet hypothyroïdien du Sunitinib, un inhibiteur de récepteurs tyrosines kinases, par approche métabonomique chez le rat [Poster presentation]. Matinée des chercheurs (MDC2015), Mons, Belgium.

Thooft, A.* , Conotte, R., Colet, J.-M., Zouaoui Boudjeltia, K., Biston, P., & Piagnerelli, M. (05 April 2023). Serum Metabolomic Profiles in Critically Ill Patients with Shock on Admission to the Intensive Care Unit. Metabolites, 13 (4), 523. doi:10.3390/metabo13040523
Peer Reviewed verified by ORBi

Grosjean, P., Engels, G., & Conotte, R. (2022). Biological data science courses at UMONS, Belgium: student's activity for 2020-2021. doi:10.5281/zenodo.6420917

Grosjean, P., Engels, G., & Conotte, R. (2022). Biological data science courses at UMONS, Belgium: student's activity for 2019-2020. doi:10.5281/zenodo.6420878

Grosjean, P., Engels, G., & Conotte, R. (2020). BioDataScience1: A Series of Learnr Documents for Biological Data Science course 1: An R package for teaching biological data science.

Devalckeneer, A., Bouviez, M., Conotte, R., & Colet, J.-M. (01 October 2019). Proton Nuclear Magnetic Resonance (1H NMR) profiling of isolated organs in the snail Helix aspersa maxima. Ecological Indicators, 105, 177-187. doi:10.1016/j.ecolind.2019.05.058
Peer reviewed

Valentini, X., Rugira Uwamahoro, P., Frau, A., Tagliatti, V., Conotte, R., Laurent, S., Colet, J.-M., & Nonclercq, D. (03 March 2019). Hepatic and renal toxicity induced by TiO2 nanoparticles in rats : a morphological and metabonomic study. Journal of Toxicology, 2019.
Peer Reviewed verified by ORBi

Devalckeneer, A., Conotte, R., Rochez, E., & Colet, J.-M. (15 December 2016). Development in invertebrate models for human healh risk assessment in the context of pollution [Poster presentation]. 6ème Congrès International de Toxicologie SMTCA, Marrakech, Morocco.

Richard, V., Conotte, R., Kindt, N., Saussez, S., & Colet, J.-M. (07 October 2016). Macrophage migration inhibitory factor (MIF) involvement in breast cancer cell metabolism: A 1H-NMR spectroscopy evaluation [Poster presentation]. ESMO 2016 Congress From disease treatment to patient care, Copenhagen, Denmark.

Delcourt, M., Tagliatti, V., Conotte, R., & Colet, J.-M. (21 September 2016). Metabonomics as an indicative tool to understand metabolic disruption linked to diet, diseases & drugs [Poster presentation]. Workshop NutriOx 2016, Kaiserslautern, Unknown/unspecified.

Tagliatti, V., Conotte, R., De Luca, D., Podrecca, M., & Colet, J.-M. (21 September 2016). Metabonomics applied to toxicology and clinical studies [Poster presentation]. Workshop NutriOx 2016, Kaiserslautern, Unknown/unspecified.

Thooft, A., Colet, J.-M., Conotte, R., Biston, P., & Piagnerelli, M. (15 December 2015). Patients' metabolomic profile in the ICU. Critical Care Medicine, 43 (12), 267-268.
Peer Reviewed verified by ORBi

Valentini, X., Rugira Uwamahoro, P., Conotte, R., Frau, A., & Nonclercq, D. (12 September 2015). Distribution of TiO2nanoparticles after intraperitoneal administration and toxicity on different target organs [Poster presentation]. BSM Annual Meeting 2015: When Materials Meet Biology, Mons, Unknown/unspecified.

Conotte, R. (22 May 2015). Hypertension et hypothyroïdisme comme biomarqueurs potentiels de l'efficacité du Sunitinib, un inhibiteur de tyrosine-kinases : Une étude mécanistique par approche métabonomique chez le rat [Paper presentation]. Première Journée d'Etudes UMHAP, Mons, Belgium.

Maroil, D., Labiau, L., Conotte, R., & Colet, J.-M. (22 May 2015). Exploration de l'effet hypothyroïdien du Sunitinib, un inhibiteur de récepteurs tyrosines kinases, par approche métabonomique chez le rat [Poster presentation]. Journée UMHAP, Mons, Belgium.

Conotte, R., Richard, V., & Colet, J.-M. (22 May 2015). Exemples d'activités de l'unité de profiling biomédical en oncologie [Poster presentation]. Première Journée d'Etudes UMHAP, Mons, Belgium.

Berkers, J. H. M., C., V., O., G., B., B., Conotte, R., Blankert, B., S., J., H., V. P., & E., L. (01 April 2015). 778 MIR-141 expression in clear cell renal cell carcinoma is linked with augmented susceptibility to sunitinib therapy in vivo. European Urology Supplements, 14 (2), 778-e778.
Peer Reviewed verified by ORBi

Conotte, R. (2015). Hypertension et hypothyroïdisme comme biomarqueurs potentiels de l'efficacité du Sunitinib, un inhibiteur de tyrosine-kinases : Une étude mécanistique par approche métabonomique chez le rat [Doctoral thesis, Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/22598

Valentini, X., Rugira, P., Conotte, R., Frau, A., & Nonclercq, D. (26 November 2014). Acute and chronic histopathological alterations related to the administration of TiO2 nanoparticles in rats [Poster presentation]. Biowin Day, Louvain-la-Neuve, Belgium.

Valentini, X., Rugira, P., Conotte, R., Frau, A., & Nonclercq, D. (07 November 2014). Acute and chronic histopathological alterations related to the administration of TiO2 nanoparticles in rats [Poster presentation]. 211th BSBMB meeting, Antwerpen, Belgium.

Soubhye, J., Prévost, M., Elfving, B., Gelbcke, M., Podrecca, M., Conotte, R., Colet, J.-M., Furtmuller, P. G., Delporte, C., Rousseau, A., Vanhaeverbeek, M., Nève, J., Obinger, C., Zouaoui Boudjeltia, K., Van Antwerpen, P., & Dufrasne, F. (2014). Hybrid Molecules Inhibiting Myeloperoxidase Activity and Serotonin Reuptake: A Possible New Approach of Major Depressive Disorders with Inflammatory Syndrome. Journal of Pharmacy and Pharmacology.

Conotte, R., & Colet, J.-M. (28 February 2014). A metabonomic evaluation of the monocrotaline-induced sinusoidal obstruction syndrome (SOS) in rats. Toxicology and Applied Pharmacology, 276 (2), 147-156.
Peer Reviewed verified by ORBi

Hambye, S., Helvenstein, M., Verdy, L., Kahvecioglu, Z. C., Conotte, R., Vanden Eynde, J.-J., Colet, J.-M., & Blankert, B. (10 February 2014). Ultra High Performance Liquid Chromatography method for the determination of Pentamidine and analog in rat biological fluids. Journal of Pharmaceutical and Biomedical Analysis, 95, 54-60.
Peer Reviewed verified by ORBi

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (29 October 2013). A similar UPLC-UV method for three tyrosine kinase inhibitors determination in human plasma [Paper presentation]. 17th Forum of Pharmaceutical Sciences, Spa, Belgium.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (30 June 2013). Ultra-performance liquid chromatography method for the determination of tyrosine kinase inhibitors in human plasma [Poster presentation]. 24th International Symposium on Pharmaceutical and Biomedical Analysis, Bologne, Italy.

Conotte, R. (31 May 2013). Métabonomique appliquée à la cancérologie [Paper presentation]. 25 e Séminaire Pédagogique - Association nationale des Professeures et Maitres de conférences biochimistes-biologistes moléculaires (ANPMCB), Guidel-Plage, France.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (24 May 2013). Tyrosine kinase inhibitors quantification by UPLC-UV in human plasma [Poster presentation]. Health Institute Day, Mons, Umons, Belgium.

Soubhye, J., Aldib, I., Elfving, B., Gelbcke, M., Furtmuller, P. G., Podrecca, M., Conotte, R., Colet, J.-M., Rousseau, A., Reyé, F., Sarakbi, A., Vanhaeverbeek, M., Kauffmann, J.-M., Obinger, C., Nève, J., Prevost, M., Zouaoui Boudjeltia, K., Dufrasne, F., & Van Antwerpen, P. (23 May 2013). Design, Synthesis, and Structure-Activity Relationship Studies of Novel 3-Alkylindole Derivatives as Selective and Highly Potent Myeloperoxidase Inhibitors. Journal of Medicinal Chemistry, 56 (10), 3943-3958. doi:10.1021/jm4001538
Peer Reviewed verified by ORBi

Bouko, Y., Conotte, R., Mayné, D., Barbouto, A.-M., Robin, V., & Colet, J.-M. (03 April 2013). A metabonomic-based strategy for the discrimination of different stages in the progression of Multiple Myeloma [Poster presentation]. 14th International Myeloma Workshop (IMW2013), Kyoto, Japan.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (12 March 2013). Tyrosine kinase inhibitors quantification in human plasma [Poster presentation]. 7ième Matinée des Chercheurs, Mons, Belgium.

Richard, V., Conotte, R., Kindt, N., Faverly, D., Laurent, G., Colet, J.-M., Noël, J. C., & Saussez, S. (29 January 2013). INTEGRATING PROTEOMICS AND METABONOMICS FOR A BETTER UNDERSTANDING OF HUMAN BREAST CANCER BIOLOGY [Poster presentation]. 1ère journée des doctorants en Sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Duquesne, M., Goossens, C., Dika, Z., Conotte, R., Nortier, J., Jelakovic, B., & Colet, J.-M. (2012). Metabonomics: on the Road to Detect Diagnostic Biomarkers in Endemic. Journal of Cancer Science and Therapy.
Peer Reviewed verified by ORBi

Richard, V., Conotte, R., Bouko, Y., & Colet, J.-M. (06 October 2012). Can 1H-NMR-based Metabonomics Identify Bad Prognosis [Paper presentation]. 29ème meeting annuel de l'European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Lisbonne, Portugal.

Richard, V., Conotte, R., Saussez, S., & Colet, J.-M. (04 October 2012). Can 1H-NMR-based Metabonomics Identify Bad Prognosis Subpopulations in Breast Cancer Patients ? [Paper presentation]. ESMRMB 2012 Congress, Lisbonne, Unknown/unspecified.

Conotte, R. (12 September 2012). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model [Paper presentation]. 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Colet, J.-M., Duquesne, M., & Conotte, R. (10 September 2012). A metabonomic Evaluation of the Balkan Endemic Nephropathy [Paper presentation]. 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Conotte, R., & Colet, J.-M. (10 September 2012). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model [Poster presentation]. 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Colet, J.-M., Duquesne, M., & Conotte, R. (10 September 2012). A metabonomic Evaluation of the Balkan Endemic Nephropathy' in 2nd World Congress on Cancer Science & Therapy [Paper presentation]. 2nd World Congress on cancer science and therapy, San Antonio, United States - Texas.

Podrecca, M., Conotte, R., De Luca, D., Tagliatti, V., & Colet, J.-M. (2012). Metabonomics Applied to Toxicology and Clinical Studies [Poster presentation]. 10th 'Oxidative stress and genotoxic response' meeting, Mons, Belgium.

Colet, J.-M., & Conotte, R. (06 October 2011). A Metabonomic Strategy to Explore Predictive Biomarkers for Sunitinib Toxicity and Efficacy in Patients with RCC [Poster presentation]. ESMRMB 2011 - 28th Annual Scientific Meeting, Leipzig, Germany.

Tagliatti, V., Conotte, R., De Luca, D., & Colet, J.-M. (28 August 2011). Valproate-induced Liver Mitochondrial Dysfunction in Rats : a Metabonomic Approach. Toxicology Letters, 205, 277.
Peer Reviewed verified by ORBi

Conotte, R., Tagliatti, V., De Luca, D., & Colet, J.-M. (28 August 2011). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model [Poster presentation]. 47th Congress of the European Societies of Toxicology, Paris, France.

Tagliatti, V., Conotte, R., De Luca, D., & Colet, J.-M. (28 August 2011). Valproate-induced Liver Mitochondrial Dysfunction in Rats : a Metabonomic Approach [Poster presentation]. 47th Congress of the European Societies of Toxicology, Paris, France.

Tagliatti, V., Conotte, R., & Colet, J.-M. (2011). An isolated and perfused organ approach to validate biomarkers of toxicity identified in metabonomics studies [Paper presentation]. 47th Congress of the European Societies of Toxicology, Paris, France. doi:10.1016/j.toxlet.2010.03.503

De Luca, D., Tagliatti, V., Conotte, R., & Colet, J.-M. (28 August 2011). Chlordecone Potentiation of Carbon Tetrachloride Toxicity : a Metabonomic-based Mechanistic Study [Poster presentation]. 47th Congress of the European Societies of Toxicology, Paris, France.

Conotte, R., De Luca, D., Tagliatti, V., & Colet, J.-M. (28 August 2011). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model. Toxicology Letters, 205, 181.
Peer Reviewed verified by ORBi

De Luca, D., Tagliatti, V., Conotte, R., & Colet, J.-M. (28 August 2011). Chlordecone Potentiation of Carbon Tetrachloride Toxicity : a Metabonomic-based Mechanistic Study. Toxicology Letters, 205, 181-S182.
Peer Reviewed verified by ORBi

Conotte, R. (18 May 2011). A Metabonomic Strategy to Explore Predictive Biomarkers for Sunitinib Toxicity and Efficacy in Patients with RCC [Poster presentation]. Second Belgian Symposium in Metabolomics and Metabonomics, Liège, Belgium.

Podrecca, M., Conotte, R., Tagliatti, V., De Luca, D., & Colet, J.-M. (22 March 2011). Application de la Métabonomique en Toxicologie [Poster presentation]. Matinée des chercheurs, UMONS, Belgium.

Tagliatti, V., Conotte, R., & Colet, J.-M. (01 July 2010). Metabonomics fingerprint of the isolated and perfused liver [Poster presentation]. XII international congress of toxicology - IUTOX 2010, Barcelone, Spain.

Tagliatti, V., Conotte, R., & Colet, J.-M. (01 June 2010). Metabonomics fingerprint of the isolated and perfused liver [Poster presentation]. Metabolomics conference 2010, Amsterdam, Netherlands.

Colet, J.-M., Conotte, R., Kahvecioglu, Z. C., & Matuszak, N. (01 September 2009). Long term metabolic changes induced inidiosyncrasy-like liver toxicity [Poster presentation]. 46th Congress of the European Societies of Toxicology - Eurotox 2009, Dresde, Germany.

Colet, J.-M., & Conotte, R. (01 September 2009). Long term metabolic changes induced indiosyncrasy-like liver toxicity. Toxicology Letters, 189S, 95-S96.
Peer Reviewed verified by ORBi

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