Profil

Conotte Raphael

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Service du Doyen de la Faculté de Médecine et Pharmacie

Université de Mons - UMONS > Faculté des Sciences > Service d'Ecologie numérique

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Service de Biochimie métabolique et moléculaire

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > Biologie humaine et Toxicologie

Université de Mons - UMONS > Faculté de Médecine et de Pharmacie > FMP - Service du Doyen


Main Referenced Co-authors
Colet, Jean-Marie  (40)
Tagliatti, Vanessa  (14)
De luca, Deborah  (9)
Blankert, Bertrand  (6)
Helvenstein, Maxime  (5)
Main Referenced Keywords
Biological Data Science (2); Data Science Teaching (2); Teaching (2); Cancer (1); Data Science (1);
Main Referenced Unit & Research Centers
UMHAP - Centre de Recherche UMONS-Ambroise Paré (14)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (19)
Architecture (10)
Oncology (8)
Radiology, nuclear medicine & imaging (8)
Immunology & infectious disease (5)

Publications (total 52)

The most downloaded
2 downloads
Devalckeneer, A., Conotte, R., Rochez, E., & Colet, J.-M. (15 December 2016). Development in invertebrate models for human healh risk assessment in the context of pollution. Poster session presented at 6ème Congrès International de Toxicologie SMTCA, Marrakech, Morocco. https://hdl.handle.net/20.500.12907/10417
The most cited
39 citations (Scopus®)
Valentini, X., Rugira Uwamahoro, P., Frau, A., Tagliatti, V., Conotte, R., Laurent, S., Colet, J.-M., & Nonclercq, D. (03 March 2019). Hepatic and renal toxicity induced by TiO2 nanoparticles in rats : a morphological and metabonomic study. Journal of Toxicology, 2019. https://hdl.handle.net/20.500.12907/19213

Maroil, D., Labiau, L., Conotte, R., & Colet, J.-M. (In press). Exploration de l'effet hypothyroïdien du Sunitinib, un inhibiteur de récepteurs tyrosines kinases, par approche métabonomique chez le rat. Poster session presented at Matinée des chercheurs (MDC2015), Mons, Belgium.

Grosjean, P., Engels, G., & Conotte, R. (2022). Biological data science courses at UMONS, Belgium: student's activity for 2020-2021. doi:10.5281/zenodo.6420917

Grosjean, P., Engels, G., & Conotte, R. (2022). Biological data science courses at UMONS, Belgium: student's activity for 2019-2020. doi:10.5281/zenodo.6420878

Grosjean, P., Engels, G., & Conotte, R. (2020). BioDataScience1: A Series of Learnr Documents for Biological Data Science course 1: An R package for teaching biological data science.

Devalckeneer, A., Bouviez, M., Conotte, R., & Colet, J.-M. (01 October 2019). Proton Nuclear Magnetic Resonance (1H NMR) profiling of isolated organs in the snail Helix aspersa maxima. ecological indicator, 105, 177-187. doi:10.1016/j.ecolind.2019.05.058
Peer reviewed

Valentini, X., Rugira Uwamahoro, P., Frau, A., Tagliatti, V., Conotte, R., Laurent, S., Colet, J.-M., & Nonclercq, D. (03 March 2019). Hepatic and renal toxicity induced by TiO2 nanoparticles in rats : a morphological and metabonomic study. Journal of Toxicology, 2019.
Peer Reviewed verified by ORBi

Devalckeneer, A., Conotte, R., Rochez, E., & Colet, J.-M. (15 December 2016). Development in invertebrate models for human healh risk assessment in the context of pollution. Poster session presented at 6ème Congrès International de Toxicologie SMTCA, Marrakech, Morocco.

Richard, V., Conotte, R., Kindt, N., Saussez, S., & Colet, J.-M. (07 October 2016). Macrophage migration inhibitory factor (MIF) involvement in breast cancer cell metabolism: A 1H-NMR spectroscopy evaluation. Poster session presented at ESMO 2016 Congress From disease treatment to patient care, Copenhagen, Denmark.

Delcourt, M., Tagliatti, V., Conotte, R., & Colet, J.-M. (21 September 2016). Metabonomics as an indicative tool to understand metabolic disruption linked to diet, diseases & drugs. Poster session presented at Workshop NutriOx 2016, Kaiserslautern, Unknown/unspecified.

Tagliatti, V., Conotte, R., De Luca, D., Podrecca, M., & Colet, J.-M. (21 September 2016). Metabonomics applied to toxicology and clinical studies. Poster session presented at Workshop NutriOx 2016, Kaiserslautern, Unknown/unspecified.

Thooft, A., Colet, J.-M., Conotte, R., Biston, P., & Piagnerelli, M. (15 December 2015). Patients' metabolomic profile in the ICU. Critical Care Medicine, 43 (12), 267-268.
Peer Reviewed verified by ORBi

Valentini, X., Rugira Uwamahoro, P., Conotte, R., Frau, A., & Nonclercq, D. (12 September 2015). Distribution of TiO2nanoparticles after intraperitoneal administration and toxicity on different target organs. Poster session presented at BSM Annual Meeting 2015: When Materials Meet Biology, Mons, Unknown/unspecified.

Conotte, R. (22 May 2015). Hypertension et hypothyroïdisme comme biomarqueurs potentiels de l'efficacité du Sunitinib, un inhibiteur de tyrosine-kinases : Une étude mécanistique par approche métabonomique chez le rat. Paper presented at Première Journée d'Etudes UMHAP, Mons, Belgium.

Maroil, D., Labiau, L., Conotte, R., & Colet, J.-M. (22 May 2015). Exploration de l'effet hypothyroïdien du Sunitinib, un inhibiteur de récepteurs tyrosines kinases, par approche métabonomique chez le rat. Poster session presented at Journée UMHAP, Mons, Belgium.

Conotte, R., Richard, V., & Colet, J.-M. (22 May 2015). Exemples d'activités de l'unité de profiling biomédical en oncologie. Poster session presented at Première Journée d'Etudes UMHAP, Mons, Belgium.

Berkers, J. H. M., C., V., O., G., B., B., Conotte, R., Blankert, B., S., J., H., V. P., & E., L. (01 April 2015). 778 MIR-141 expression in clear cell renal cell carcinoma is linked with augmented susceptibility to sunitinib therapy in vivo. European Urology Supplements, 14 (2), 778-e778.
Peer Reviewed verified by ORBi

Conotte, R. (2015). Hypertension et hypothyroïdisme comme biomarqueurs potentiels de l'efficacité du Sunitinib, un inhibiteur de tyrosine-kinases : Une étude mécanistique par approche métabonomique chez le rat. Unpublished doctoral thesis, Université de Mons.
Jury: Colet, J.-M. (Promotor), Blankert, B., Vander Elst, L., Nonclercq, D., Declèves, A.-E., ... Van den Hove, L.

Valentini, X., Rugira, P., Conotte, R., Frau, A., & Nonclercq, D. (26 November 2014). Acute and chronic histopathological alterations related to the administration of TiO2 nanoparticles in rats. Poster session presented at Biowin Day, Louvain-la-Neuve, Belgium.

Valentini, X., Rugira, P., Conotte, R., Frau, A., & Nonclercq, D. (07 November 2014). Acute and chronic histopathological alterations related to the administration of TiO2 nanoparticles in rats. Poster session presented at 211th BSBMB meeting, Antwerpen, Belgium.

Soubhye, J., Prévost, M., Elfving, B., Gelbcke, M., Podrecca, M., Conotte, R., Colet, J.-M., Furtmuller, P. G., Delporte, C., Rousseau, A., Vanhaeverbeek, M., Nève, J., Obinger, C., Zouaoui Boudjeltia, K., Van Antwerpen, P., & Dufrasne, F. (2014). Hybrid Molecules Inhibiting Myeloperoxidase Activity and Serotonin Reuptake: A Possible New Approach of Major Depressive Disorders with Inflammatory Syndrome. Journal of Pharmacy and Pharmacology.

Conotte, R., & Colet, J.-M. (28 February 2014). A metabonomic evaluation of the monocrotaline-induced sinusoidal obstruction syndrome (SOS) in rats. Toxicology and Applied Pharmacology, 276 (2), 147-156.
Peer Reviewed verified by ORBi

Hambye, S., Helvenstein, M., Verdy, L., Kahvecioglu, Z. C., Conotte, R., Vanden Eynde, J.-J., Colet, J.-M., & Blankert, B. (10 February 2014). Ultra High Performance Liquid Chromatography method for the determination of Pentamidine and analog in rat biological fluids. Journal of Pharmaceutical and Biomedical Analysis, 95, 54-60.
Peer Reviewed verified by ORBi

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (29 October 2013). A similar UPLC-UV method for three tyrosine kinase inhibitors determination in human plasma. Paper presented at 17th Forum of Pharmaceutical Sciences, Spa, Belgium.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (30 June 2013). Ultra-performance liquid chromatography method for the determination of tyrosine kinase inhibitors in human plasma. Poster session presented at 24th International Symposium on Pharmaceutical and Biomedical Analysis, Bologne, Italy.

Conotte, R. (31 May 2013). Métabonomique appliquée à la cancérologie. Paper presented at 25 e Séminaire Pédagogique - Association nationale des Professeures et Maitres de conférences biochimistes-biologistes moléculaires (ANPMCB), Guidel-Plage, France.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (24 May 2013). Tyrosine kinase inhibitors quantification by UPLC-UV in human plasma. Poster session presented at Health Institute Day, Mons, Umons, Belgium.

Soubhye, J., Aldib, I., Elfving, B., Gelbcke, M., Furtmuller, P. G., Podrecca, M., Conotte, R., Colet, J.-M., Rousseau, A., Reyé, F., Sarakbi, A., Vanhaeverbeek, M., Kauffmann, J.-M., Obinger, C., Nève, J., Prevost, M., Zouaoui Boudjeltia, K., Dufrasne, F., & Van Antwerpen, P. (23 May 2013). Design, Synthesis, and Structure-Activity Relationship Studies of Novel 3-Alkylindole Derivatives as Selective and Highly Potent Myeloperoxidase Inhibitors. Journal of Medicinal Chemistry, 56 (10), 3943-3958. doi:10.1021/jm4001538
Peer Reviewed verified by ORBi

Bouko, Y., Conotte, R., Mayné, D., Barbouto, A.-M., Robin, V., & Colet, J.-M. (03 April 2013). A metabonomic-based strategy for the discrimination of different stages in the progression of Multiple Myeloma. Poster session presented at 14th International Myeloma Workshop (IMW2013), Kyoto, Japan.

Helvenstein, M., Conotte, R., Colet, J.-M., & Blankert, B. (12 March 2013). Tyrosine kinase inhibitors quantification in human plasma. Poster session presented at 7ième Matinée des Chercheurs, Mons, Belgium.

Richard, V., Conotte, R., Kindt, N., Faverly, D., Laurent, G., Colet, J.-M., Noël, J. C., & Saussez, S. (29 January 2013). INTEGRATING PROTEOMICS AND METABONOMICS FOR A BETTER UNDERSTANDING OF HUMAN BREAST CANCER BIOLOGY. Poster session presented at 1ère journée des doctorants en Sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Duquesne, M., Goossens, C., Dika, Z., Conotte, R., Nortier, J., Jelakovic, B., & Colet, J.-M. (2012). Metabonomics: on the Road to Detect Diagnostic Biomarkers in Endemic. Journal of Cancer Science & Therapy.
Peer Reviewed verified by ORBi

Richard, V., Conotte, R., Bouko, Y., & Colet, J.-M. (06 October 2012). Can 1H-NMR-based Metabonomics Identify Bad Prognosis. Paper presented at 29ème meeting annuel de l'European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Lisbonne, Portugal.

Richard, V., Conotte, R., Saussez, S., & Colet, J.-M. (04 October 2012). Can 1H-NMR-based Metabonomics Identify Bad Prognosis Subpopulations in Breast Cancer Patients ? Paper presented at ESMRMB 2012 Congress, Lisbonne, Unknown/unspecified.

Conotte, R. (12 September 2012). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model. Paper presented at 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Colet, J.-M., Duquesne, M., & Conotte, R. (10 September 2012). A metabonomic Evaluation of the Balkan Endemic Nephropathy. Paper presented at 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Conotte, R., & Colet, J.-M. (10 September 2012). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model. Poster session presented at 2nd World Congress on Cancer Science & Therapy, San Antonio, United States - Texas.

Colet, J.-M., Duquesne, M., & Conotte, R. (10 September 2012). A metabonomic Evaluation of the Balkan Endemic Nephropathy' in 2nd World Congress on Cancer Science & Therapy. Paper presented at 2nd World Congress on cancer science and therapy, San Antonio, United States - Texas.

Podrecca, M., Conotte, R., De Luca, D., Tagliatti, V., & Colet, J.-M. (2012). Metabonomics Applied to Toxicology and Clinical Studies. Poster session presented at 10th 'Oxidative stress and genotoxic response' meeting, Mons, Belgium.

Colet, J.-M., & Conotte, R. (06 October 2011). A Metabonomic Strategy to Explore Predictive Biomarkers for Sunitinib Toxicity and Efficacy in Patients with RCC. Poster session presented at ESMRMB 2011 - 28th Annual Scientific Meeting, Leipzig, Germany.

Tagliatti, V., Conotte, R., De Luca, D., & Colet, J.-M. (28 August 2011). Valproate-induced Liver Mitochondrial Dysfunction in Rats : a Metabonomic Approach. Toxicology Letters, 205, 277.
Peer Reviewed verified by ORBi

Conotte, R., Tagliatti, V., De Luca, D., & Colet, J.-M. (28 August 2011). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model. Poster session presented at 47th Congress of the European Societies of Toxicology, Paris, France.

Tagliatti, V., Conotte, R., De Luca, D., & Colet, J.-M. (28 August 2011). Valproate-induced Liver Mitochondrial Dysfunction in Rats : a Metabonomic Approach. Poster session presented at 47th Congress of the European Societies of Toxicology, Paris, France.

Tagliatti, V., Conotte, R., & Colet, J.-M. (2011). An isolated and perfused organ approach to validate biomarkers of toxicity identified in metabonomics studies. Paper presented at 47th Congress of the European Societies of Toxicology, Paris, France. doi:10.1016/j.toxlet.2010.03.503

De Luca, D., Tagliatti, V., Conotte, R., & Colet, J.-M. (28 August 2011). Chlordecone Potentiation of Carbon Tetrachloride Toxicity : a Metabonomic-based Mechanistic Study. Poster session presented at 47th Congress of the European Societies of Toxicology, Paris, France.

Conotte, R., De Luca, D., Tagliatti, V., & Colet, J.-M. (28 August 2011). Metabonomic Evaluation of Oxaliplatin Hepatotoxicity by Comparison with a Sinusoidal Obstruction Syndrome (SOS) Model. Toxicology Letters, 205, 181.
Peer Reviewed verified by ORBi

De Luca, D., Tagliatti, V., Conotte, R., & Colet, J.-M. (28 August 2011). Chlordecone Potentiation of Carbon Tetrachloride Toxicity : a Metabonomic-based Mechanistic Study. Toxicology Letters, 205, 181-S182.
Peer Reviewed verified by ORBi

Conotte, R. (18 May 2011). A Metabonomic Strategy to Explore Predictive Biomarkers for Sunitinib Toxicity and Efficacy in Patients with RCC. Poster session presented at Second Belgian Symposium in Metabolomics and Metabonomics, Liège, Belgium.

Podrecca, M., Conotte, R., Tagliatti, V., De Luca, D., & Colet, J.-M. (22 March 2011). Application de la Métabonomique en Toxicologie. Poster session presented at Matinée des chercheurs, UMONS, Belgium.

Tagliatti, V., Conotte, R., & Colet, J.-M. (01 July 2010). Metabonomics fingerprint of the isolated and perfused liver. Poster session presented at XII international congress of toxicology - IUTOX 2010, Barcelone, Spain.

Tagliatti, V., Conotte, R., & Colet, J.-M. (01 June 2010). Metabonomics fingerprint of the isolated and perfused liver. Poster session presented at Metabolomics conference 2010, Amsterdam, Netherlands.

Colet, J.-M., Conotte, R., Kahvecioglu, Z. C., & Matuszak, N. (01 September 2009). Long term metabolic changes induced inidiosyncrasy-like liver toxicity. Poster session presented at 46th Congress of the European Societies of Toxicology - Eurotox 2009, Dresde, Germany.

Colet, J.-M., & Conotte, R. (01 September 2009). Long term metabolic changes induced indiosyncrasy-like liver toxicity. Toxicology Letters, 189S, 95-S96.
Peer Reviewed verified by ORBi

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