Article (Scientific journals)
Polyelectrolyte complexes based on (quaternized) poly[2-dimethylamino)ethyl methacrylate] : behaviour in contact with blood
Yancheva, Elena; Paneva, Dilyana; Danchev, Dobri et al.
2007In Macromolecular Bioscience, 7 (7-8), p. 940-954
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Abstract :
[en] Polyelectrolyte complexes (PECs) between (quaternized) poly[2-(dimethylamino)ethyl methacrylate] (PDMAEMA) and (crosslinked) N-carboxyethylchitosan (CECh) or poly(2-acrylamido-2-methylpropane sodium sulfonate) (PAMPSNa) were prepared and characterized in terms of their stability, equilibrium water content, and surface morphology. The evaluation of the behavior of the studied PECs in contact with blood revealed that the (crosslinked) CECh/(quaternized) PDMAEMA complexes had lost the inherent PDMAEMA cytotoxicity but still preserved haemostatic activity. In contrast, the complex formation between (quaternized) PDMAEMA and PAMPSNa allowed the preparation of materials with improved blood compatibility.
Disciplines :
Chemistry
Author, co-author :
Yancheva, Elena
Paneva, Dilyana
Danchev, Dobri
Mespouille, Laetitia 
Dubois, Philippe  ;  Université de Mons > Faculté des Sciences > Matériaux Polymères et Composites
Manolova, Nevena
Rashkov, Iliya
Language :
English
Title :
Polyelectrolyte complexes based on (quaternized) poly[2-dimethylamino)ethyl methacrylate] : behaviour in contact with blood
Publication date :
09 July 2007
Journal title :
Macromolecular Bioscience
ISSN :
1616-5187
eISSN :
1616-5195
Publisher :
John Wiley & Sons, United Kingdom
Volume :
7
Issue :
7-8
Pages :
940-954
Peer reviewed :
Peer Reviewed verified by ORBi
Research unit :
S816 - Matériaux Polymères et Composites
Research institute :
R400 - Institut de Recherche en Science et Ingénierie des Matériaux
Commentary :
Publié en ligne le 19 juin 2007 Lecture en ligne: http://onlinelibrary.wiley.com/doi/10.1002/mabi.200700056/pdf
Available on ORBi UMONS :
since 10 July 2010

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