Improving the spectrophotometric determination of the alkylating activity of anticancer agents : a new insight into the mechanism of the NBP method

Dierickx, Karen ME; Journé, Fabrice; Gerbaux, Pascal; Morandini, Renato; Kauffmann, Jean-Michel; Ghanem, Ghanem E

Article (Scientific journals)

Dierickx, Karen ME; Journé, Fabrice; Gerbaux, Pascal et al.

2009 • In Talanta, 77 (4), p. 1370-1375

Peer Reviewed verified by ORBi

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https://hdl.handle.net/20.500.12907/23233

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19084651

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Abstract :

[en] In this paper, the mechanism of the nitrobenzylpyridine (NBP) method to measure the alkylating activity of drugs originally described by Epstein et al. IJ. Epstein, R.W. Rosenthal, R.J. Ess, Anal. Chem. 27 (1955) 1435-1439] and modified later by others wa

Disciplines :

Chemistry

Author, co-author :

Dierickx, Karen ME

Journé, Fabrice

Gerbaux, Pascal ; Université de Mons > Faculté des Sciences > Synthèse et spectrométrie de masse organiques

Morandini, Renato

Kauffmann, Jean-Michel

Ghanem, Ghanem E

Language :

English

Title :

Improving the spectrophotometric determination of the alkylating activity of anticancer agents : a new insight into the mechanism of the NBP method

Publication date :

01 January 2009

Journal title :

Talanta

ISSN :

0039-9140

Publisher :

Elsevier, Netherlands

Volume :

Issue :

Pages :

1370-1375

Peer reviewed :

Peer Reviewed verified by ORBi

Research unit :

S836 - Synthèse et spectrométrie de masse organiques

Available on ORBi UMONS :

since 10 July 2010

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