A High-Performance Magnetic Resonance Imaging T2 Contrast Agent

Qin, J.; Laurent, Sophie; Jo, Y.S.; Roch, Alain; Mikhaylova, M.; Bhujwalla, Z.M.; Muller, Robert; Muhammed, M.

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A High-Performance Magnetic Resonance Imaging T2 Contrast Agent

Qin, J.; Laurent, Sophie; Jo, Y.S. et al.

2007 • In Advanced Materials, 19 (14), p. 1874-1878

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Abstract :

A high-performance magnetic resonance imaging T2 contrast agent has been prepared via phase transfer of hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) to an aqueous solution by using Pluronic?F127 copolymers. As seen in the figure, a hierarchical structure of the surface coating is formed and proven to be a crucial characteristic to enhance not only water dispersibility, but also the efficacy as a T2 contrast agent.

Research center :

CMMI - Centre de Recherche en Microscopie et Imagerie Médicale

Disciplines :

Chemistry

Author, co-author :

Qin, J.

Laurent, Sophie ; Université de Mons > Faculté de Médecine et de Pharmacie > Chimie générale, organique et biomédicale

Jo, Y.S.

Roch, Alain

Mikhaylova, M.

Bhujwalla, Z.M.

Muller, Robert ; Université de Mons > Faculté de Médecine et de Pharmacie > Chimie générale, organique et biomédicale

Muhammed, M.

Language :

English

Title :

A High-Performance Magnetic Resonance Imaging T2 Contrast Agent

Publication date :

01 January 2007

Journal title :

Advanced Materials

ISSN :

0935-9648

eISSN :

1521-4095

Publisher :

Wiley-Blackwell, United States

Volume :

Issue :

Pages :

1874-1878

Peer reviewed :

Peer Reviewed verified by ORBi

Research unit :

M108 - Chimie générale, organique et biomédicale

Research institute :

R550 - Institut des Sciences et Technologies de la Santé
R100 - Institut des Biosciences

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Scopus citations^®

231

Scopus citations^®
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219

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