Sensibility, specificity, and accuracy of the Sinonasal Outcome Test 8 (SNOT-8) in patients with chronic rhinosinusitis (CRS): a cross-sectional cohort study.
La Mantia, Ignazio; Ragusa, Martina; Grigaliute, Egleet al.
2023 • In European Archives of Oto-Rhino-Laryngology, 280 (7), p. 3259 - 3264
Chronic rhinosinusitis with nasal polyps; HRQoL; NPS; SNOT-22; Adult; Humans; Sino-Nasal Outcome Test; Prospective Studies; Cross-Sectional Studies; Chronic Disease; Quality of Life; Rhinitis/diagnosis; Rhinitis/surgery; Nasal Polyps/surgery; Sinusitis/diagnosis; Sinusitis/surgery; Nasal Polyps; Rhinitis; Sinusitis; Otorhinolaryngology; General Medicine
Abstract :
[en] [en] PURPOSE: To analyze as the primary endpoint the accuracy, sensitivity, and specificity of the SNOT-22 assessing CRS severity and to compare the results with a version of the SNOT-8 obtained from the nasal domain items.
METHODS: Data were obtained from a prospective multicenter controlled study of dupilumab in adults with moderate-severe CRSwNP. EQUATOR and STROBE network guidelines were adopted. A multivariate logistic regression model was used to evaluate the accuracy of the model with the full (SNOT-22) and reduced (SNOT-8) item set to predict the severity outcome.
RESULTS: SNOT-22 demonstrated an AUC of 0.885 (95% CI 0.825, - 0.945), and sensitivity and specificity of 91.49% (83.92-96.25%) and 69.23% (48.21-85.67%), respectively. Interestingly, after stepwise items elimination good outcomes were reported for SNOT-8, with an AUC of 0.818 (95% CI 0.744-0.892), achieving a sensitivity of 93.51% (85.49-97.86%) and specificity of 57.14% (40.96-72.28%).
CONCLUSION: Psychometric analyses support the accuracy, sensitivity, and specificity of the nasal domains of SNOT-22 to assess the impact on HRQoL in patients with CRSwNP.
Disciplines :
Otolaryngology
Author, co-author :
La Mantia, Ignazio; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123, Catania, Italy
Ragusa, Martina; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123, Catania, Italy
Grigaliute, Egle; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123, Catania, Italy
Cocuzza, Salvatore; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123, Catania, Italy
Radulesco, Thomas; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France ; Department of Oto-Rhino-Laryngology Head and Neck Surgery, Aix-Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, 13000, France
Calvo-Henriquez, Christian; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France
Saibene, Alberto Maria; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France ; Otolaryngology Unit Santi Paolo e Carlo Hospital Department of Health Sciences, Università degli Studi di Milano, Milan, 20100, Italy
Riela, Paolo Marco; Department of Mathematics and Informatics, University of Catania, 95123, Catania, Italy
Lechien, Jérome ; Université de Mons - UMONS > Faculté de Psychologie et des Sciences de l'Educatio > Service de Métrologie et Sciences du langage
Fakhry, Nicolas; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France ; Department of Oto-Rhino-Laryngology Head and Neck Surgery, Aix-Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, 13000, France
Michel, Justin; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France ; Department of Oto-Rhino-Laryngology Head and Neck Surgery, Aix-Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, 13000, France
Maniaci, Antonino ; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia" ENT Section, University of Catania, 95123, Catania, Italy. antonino.maniaci@phd.unict.it ; Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, 75000, France. antonino.maniaci@phd.unict.it ; Department of Oto-Rhino-Laryngology Head and Neck Surgery, Aix-Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, 13000, France. antonino.maniaci@phd.unict.it
Language :
English
Title :
Sensibility, specificity, and accuracy of the Sinonasal Outcome Test 8 (SNOT-8) in patients with chronic rhinosinusitis (CRS): a cross-sectional cohort study.
Publication date :
July 2023
Journal title :
European Archives of Oto-Rhino-Laryngology
ISSN :
0937-4477
eISSN :
1434-4726
Publisher :
Springer Science and Business Media Deutschland GmbH, Germany
Antonino M, Nicolò M, Jerome Renee L et al (2022) Single-nucleotide polymorphism in chronic rhinosinusitis: a systematic review. Clin Otolaryngol 47(1):14–23. 10.1111/coa.13870 DOI: 10.1111/coa.13870
Schlosser RJ, Gage SE, Kohli P, Soler ZM (2016) Burden of illness: a systematic review of depression in chronic rhinosinusitis. Am J Rhinol Allergy 30(4):250–256. 10.2500/ajra.2016.30.4343 DOI: 10.2500/ajra.2016.30.4343
DeConde AS, Mace JC, Bodner T et al (2014) SNOT-22 quality of life domains differentially predict treatment modality selection in chronic rhinosinusitis. Int Forum Allergy Rhinol 4(12):972–979. 10.1002/alr.21408 DOI: 10.1002/alr.21408
Schneider S, Campion NJ, Villazala-Merino S et al (2020) Associations between the quality of life and nasal polyp size in patients suffering from chronic rhinosinusitis without nasal polyps, with nasal polyps or aspirin-exacerbated respiratory disease. J Clin Med 9(4):925. 10.3390/jcm9040925 DOI: 10.3390/jcm9040925
Klonaris DA, Doulaptsi M, Karatzanis A, Velegrakis S, Milioni A, Prokopakis E (2019) Assessing quality of life and burden of disease in chronic rhinosinusitis: a review. Rhinology
Liu DT, Phillips KM, Speth MM, Besser G, Mueller CA, Sedaghat AR (2022) Item response theory for psychometric properties of the SNOT-22 (22-Item Sinonasal Outcome Test). Otolaryngol Head Neck Surg 166(3):580–588. 10.1177/01945998211018383 DOI: 10.1177/01945998211018383
Bachert C et al (2019) Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet 394(10209):1638–1650. 10.1016/S0140-6736(19)31881-1 DOI: 10.1016/S0140-6736(19)31881-1
Garbutt J, Spitznagel E, Piccirillo J (2011) Use of the modified SNOT-16 in primary care patients with clinically diagnosed acute rhinosinusitis. Arch Otolaryngol Head Neck Surg 137(8):792–797 DOI: 10.1001/archoto.2011.120
von Elm E, Altman DG, Egger M et al (2014) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies. Int J Surg 12(12):1495–1499. 10.1016/j.ijsu.2014.07.013 DOI: 10.1016/j.ijsu.2014.07.013
Meltzer EO, Hamilos DL, Hadley JA et al (2004) Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114(6 Suppl):155–212. 10.1016/j.jaci.2004.09.029 DOI: 10.1016/j.jaci.2004.09.029
Fokkens WJ, Lund VJ, Hopkins C et al (2020) European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 58(Suppl S29):1–464. 10.4193/Rhin20.600 DOI: 10.4193/Rhin20.600
Speth MM et al (2018) Changes in chronic rhinosinusitis symptoms differentially associate with improvement in general health-related quality of life. Ann Allergy Asthma Immunol 121(2):195–199. 10.1016/j.anai.2018.05.029 DOI: 10.1016/j.anai.2018.05.029
Kennedy JL, Hubbard MA, Huyett P, Patrie JT, Borish L, Payne SC (2013) Sino-nasal outcome test (SNOT-22): a predictor of postsurgical improvement in patients with chronic sinusitis. Ann Allergy Asthma Immunol 111(4):246-251.e2. 10.1016/j.anai.2013.06.033 DOI: 10.1016/j.anai.2013.06.033
Buckland JR, Thomas S, Harries PG (2003) Can the sino-nasal Outcome test (SNOT-22) be used as a reliable outcome measure for successful septal surgery? Clin Otolaryngol Allied Sci 28:43–47 DOI: 10.1046/j.1365-2273.2003.00663.x
de los Santos G, Reyes P, del Castillo R et al (2015) Cross-cultural adaptation and validation of the sino-nasal outcome test (SNOT22) for Spanish-speaking patients. Eur Arch Otorhinolaryngology 272:3335–3340 DOI: 10.1007/s00405-014-3437-0
Koskinen A, Hammarén-Malmi S, Myller J et al (2021) Translation, cross-cultural adaptation, and validation of the sino-nasal outcome test (snot)-22 for Finnish patients. Eur Arch Otorhinolaryngol 278(2):405–410. 10.1007/s00405-020-06297-w DOI: 10.1007/s00405-020-06297-w
Asiri M, Alokby G (2019) Validation and Cross-cultural Adaptation of the Sinonasal Outcome Test (SNOT)-22 for the Arabian Patient Population. Cureus 11(4):e4447. 10.7759/cureus.4447 DOI: 10.7759/cureus.4447
Vaitkus S, Padervinskis E, Balsevicius T et al (2013) Translation, Cross-cultural adaptation, and validation of the sino-nasal outcome Test (SNOT)-22 for lithuanian patients. Eur Arch Otorhinolaryngol 270:1843–1848 DOI: 10.1007/s00405-012-2282-2
Mozzanica F, Preti A, Gera R et al (2017) Cross-cultural adaptation and validation of the SNOT-22 into italian. Eur Arch Otorhinolaryngol 274:887–895 DOI: 10.1007/s00405-016-4313-x
Ryan WR, Ramachandra T, Hwang PH (2011) Correlations between symptoms, nasal endoscopy, and in-ofce computed tomography in post-surgical chronic rhinosinusitis patients. Laryngoscope 121:674–678 DOI: 10.1002/lary.21394
Wabnitz DA, Nair S, Wormald PJ (2005) Correlation between preoperative symptom scores, quality-of-life questionnaires, and staging with computed tomography in patients with chronic rhinosinusitis. Am J Rhinol 19:91–99 DOI: 10.1177/194589240501900116
Chowdhury NI, Mace JC, Bodner TE et al (2017) Investigating the minimal clinically important difference for SNOT-22 symptom domains in surgically managed chronic rhinosinusitis. Int Forum Allergy Rhinol 7(12):1149–1155. 10.1002/alr.22028 DOI: 10.1002/alr.22028
Speth MM, Gaudin RA, Hoehle LP et al (2018) Reciprocal predictive accuracy of sinonasal symptom severity, nasal endoscopy, and frequency of past chronic rhinosinusitis exacerbations. Otolaryngol Head Neck Surg 159(4):766–773. 10.1177/0194599818774741 DOI: 10.1177/0194599818774741
Gray ST, Phillips KM, Hoehle LP, Caradonna DS, Sedaghat AR (2017) The 22-item Sino-Nasal Outcome Test accurately reflects patient-reported control of chronic rhinosinusitis symptomatology. Int Forum Allergy Rhinol 7(10):945–951. 10.1002/alr.21992 DOI: 10.1002/alr.21992
